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MICROTUBULE BASED TRANSPORT IN EARLY EMBRYOS

MICROTUBULE BASED TRANSPORT IN EARLY EMBRYOS
早期胚胎中基于微管的运输
批准号:
6019261
负责人:
Jonathan M. Scholey
金额:
$24.87万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-07-01 至 2001-06-30

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中文摘要
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英文摘要
DESCRIPTION: This application is focused on the analysis of mechanisms and functions of MT-based motors that the investigators postulate drive specific transport event that occurs during early development. They propose to : 1) characterize the structure, function and domain organization of a putative minus-end-directed kinesin holoenzyme and to analyze its role in nuclear transport and mitosis; 2) to further analyze structure-function relationships in the morphogenesis and function of mitotic spindles; 3) to biochemically characterize the vesicular cargo of the sea urchin embryonic mitotic spindle for delivery to different destinations and 4) to purify the Drosophila Nod chromosomal kinesin-like motor from transgenic fly lines, in order to analyze the mechanism by which it transports chromosomes along MTs.
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会议论文
Dynamics and Mechanics of Mitosis in Drosophila.
  • 批准号:
    7931676
  • 项目类别:
  • 资助金额:
    $8.73万
  • 财政年份:
    2009
  • 负责人:
    Jonathan M. Scholey
  • 依托单位:
MICROTUBULE BASED TRANSPORT IN EARLY EMBRYOS
  • 批准号:
    2734831
  • 项目类别:
  • 资助金额:
    $24.16万
  • 财政年份:
    1997
  • 负责人:
    Jonathan M. Scholey
  • 依托单位:
Mitotic Motors in the Drosophila Embryo.
  • 批准号:
    6606991
  • 项目类别:
  • 资助金额:
    $29.7万
  • 财政年份:
    1997
  • 负责人:
    Jonathan M. Scholey
  • 依托单位:
Dynamics and Mechanics of Mitosis in Drosophila
  • 批准号:
    7142325
  • 项目类别:
  • 资助金额:
    $31.44万
  • 财政年份:
    1997
  • 负责人:
    Jonathan M. Scholey
  • 依托单位:
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