RESEARCH TRAINING IN ACADEMIC CARDIOLOGY

本申请请求继续支持埃默里大学医学院心脏病学部心血管研究博士后培养计划。拟议的项目将建立在一个已经成功的以实验室为基础的基础科学课程的基础上，该课程在培养优秀的博士后研究员方面取得了令人印象深刻的记录。心脏病学研究部门已成为公认的研究氧化应激在血管疾病中的作用的领导者。该计划的学员在获得学术独立职位方面非常成功。我们项目的13名毕业生在美国医学院担任教职，其中7人在他们的祖国担任教职。我们有几位研究员获得了国家青年研究者奖的获奖者或决赛选手。在过去的5年里，在这个项目中训练的研究员的360多篇论文在同行评议的期刊上发表。第1年有4名基础科学研究员，第2年有3名基础科学研究员，每年有7名基础科学研究员。另外，每年申请1名临床研究员一年的资助。本次申请的17位导师提供了一个基础广泛的多学科环境，非常适合为学员提供出色的教育体验。参与的教师来自埃默里大学的心脏病学、皮肤病学、血液学/肿瘤学、生物化学、生物工程和产科/妇科。它们都有既定的资助和出版记录，以及在培训科学界富有成效的成员方面的成功记录。培训项目以导师为基础的环境为基础，辅以广泛的教学教育机会。总之，拟议的心血管研究培训计划将为基础和临床血管生物学的多学科培训提供独特的机会。成功的学员将有充分的准备开始学术心脏病学的研究生涯。

This application requests continued support for the postdoctoral training program in cardiovascular research in the Division of Cardiology at Emory University School of Medicine. The proposed program will build on an already successful laboratory-based basic science curriculum that has developed an impressive record of training outstanding postdoctoral fellows. The Cardiology Research Division has become recognized as a leader in research on the role of oxidative stress in vascular disease. The trainees of this program have been extremely successful in obtaining independent positions in academics. Thirteen graduates of our program are faculty members in American medical schools, and seven have taken faculty positions in their home countries. We have had several fellows who have been winners or finalists for national young investigator awards. In the past 5 years, over 360 manuscripts from fellows trained in this program were published in peer-reviewed journals. Two years of funding is requested for 4 basic science fellows in year 1 and 3 basic science fellows in year 2, for a total of 7 basic science fellows in any given year. In addition, one year of support is requested for 1 clinical research fellow every year. The 17 mentors included in this application provide a broad-based multi- disciplinary environment ideally suited to provide an outstanding educational experience for trainees. Participating faculty are drawn from the Divisions/Departments of Cardiology, Dermatology, Hematology/Oncology, Biochemistry, Bioengineering and Obstetrics/Gynecology at Emory University. All have an established funding and publication record as well as documented success in training productive members of the scientific community. The training program is structured around a mentor-based environment supplemented with an extensive array of didactic educational opportunities. In summary, the proposed cardiovascular research training program will provide a unique opportunity for multi-disciplinary training in basic and clinical vascular biology. Successful trainees will be well-equipped to initiate a research career in academic cardiology.