IMPAIRED AND PRESERVED MEMORY PROCESSES IN AMNESIA

描述(申请者摘要)：该项目关注的是一个信息 健忘症患者功能受损与完整的加工分析 关于言语记忆任务，目的是指定记忆的性质 依赖和不依赖于内侧颞叶和间脑的突起 健忘症时大脑结构受损。该提案的第一部分 详细探讨了健忘症中的内隐记忆现象 特别是关于健忘症患者对新形成的记忆进行启动的能力 言语联想。为了指定哪些形式的关联 学习依赖于内侧的颞叶和间脑区域， 研究人员将系统地调查健忘症患者的表现 内隐记忆任务的范围，其中新的联想启动发生在 感知的、词汇的或概念的层次。本部分的第二部分 该提案关注健忘症患者在外显记忆任务上的表现，以及 检查基于熟悉度的外显记忆是否受损到相同程度 广度是基于回忆的外显记忆。研究人员解决了 这个问题是通过直接测量记忆和熟悉度 单一任务，无论是基础流程还是相关级别 意识。他们还将检查健忘症患者是否在 不同的外显记忆任务被认为在它们的 潜在的处理需求。最后，他们将检查对 健忘症患者在几种选择性影响的操作中的表现 回忆。本提案的第三部分将审查 记忆错觉在健忘症中的发生 外显和内隐记忆，这一系列研究提供了一个链接 这项提案中的另外两条研究路线。

DESCRIPTION (Applicant's Abstract): This project focuses on an information processing analysis of the amnesic patient's impaired and intact performance on verbal memory tasks, with the goal of specifying the nature of the memory processes that do and do not depend on the medial temporal and diencephalic brain structures damaged in amnesia. The first section of this proposal explores in detail the phenomenon of implicit memory in amnesia and focuses specifically on amnesiacs' ability to demonstrate priming for newly formed verbal associations. In order to specify which forms of associative learning depend on the medial temporal and diencephalic regions, the researchers will systematically investigate amnesiacs' performance across a range of implicit memory tasks in which new associative priming occurs at a perceptual, lexical, or conceptual level. The second section of this proposal focuses on amnesiacs' performance on explicit memory tasks and examines whether familiarity-based explicit memory is impaired to the same extent as is recollection-based explicit memory. The researchers address this question by directly measuring recollection and familiarity within a single task, both in terms of underlying processes and associated levels of awareness. They will also examine whether amnesiacs are equally impaired on different explicit memory tasks that are thought to differ in their underlying processing demands. Finally, they will examine the effect on amnesiacs' performance of several manipulations that selectively influence recollection. The third section of this proposal will examine the occurrence of memory illusions in amnesia by using a paradigm in both explicit and implicit memory, this line of studies provides a link to the other two lines of studies in this proposal.