CRYSTALLOGRAPHIC STUDIES OF CYTOKINE RECEPTOR ECTODOMAIN & EXOGLUCANASE

这种细胞因子受体结合了一种重要的细胞因子，参与了 不同的细胞调节活动。这种结构将会有所帮助 了解与细胞活动相关的细胞因子，或许 能够调节这一活动。晶体已经在一种 晶胞边缘为50x50x300A的四方空间群晶体 对辐射非常敏感，目前的冷冻技术已经导致 晶格中的某种无序。两个小时的曝光 旋转阳极的衍射数据最高可达3.5A。预计 APS可以获得比3A更好的数据。

This cytokine receptor binds an important cytokine involved in diverse cellular regulatory activity. The structure will help understanding the cytokinefs related cellular activity and perhaps able to modulate this activity. Crystals have been grown in a tetragonal space group with cell edges 50 x 50 x 300 A. Crystals are very radiation sensitive, and current freezing techniques have caused some kind of disorder in the lattice. Two hour exposures on a rotating anode give diffraction data up to 3.5A. It is expected that better than 3A data can be obtained at the APS.