BIOCHEMICAL TOXICOLOGY MECHANISMS RESEARCH

生化毒理学机制研究

• 批准号: 2872294
• 负责人: Steven D Cohen
• 金额: $ 14.96万
• 依托单位: UNIVERSITY OF CONNECTICUT STORRS
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2872294
• 关键词: BIOCHEMICAL; TOXICOLOGY; MECHANISMS; RESEARCH

DESCRIPTION This application is the third revision of a renewal application for a training grant to support 4 predoctoral and 2 postdoctoral students per year. The objective of the program is to train environmental toxicologists who will use modern chemical and biochemical research techniques to define toxic injury and explore mechanisms of toxicant action. The program, while focused within the pharmacology and toxicology Ph.D. program, also includes students with strong biology or chemistry training who may be enrolled in other programs within the home departments of their mentors. It is proposed that full time University of Connecticut faculty representing 8 departments in 4 colleges and 10 toxicologists from the private sector will serve as program faculty. Students will take a core curriculum of advanced courses in toxicology, pharmacology, pathology, molecular biology and statistics, as well as individualized electives. Toxicology students must pass a series of comprehensive written and oral exams and publicly defend their dissertation research. Research training begins early in the program and progresses to near full time by the end of the 3rd year. For postdoctoral trainees, limited coursework may be required, depending upon background. All trainees will be required to participate in seminars, journal club and the toxicology scholars colloquium, to present their research at national or regional meetings, and to publish in toxicology-related journals.

本申请是第三次修订培训补助金续期申请，每年资助4名博士后和2名博士后。该计划的目标是培训环境毒物学家，他们将使用现代化学和生物化学研究技术来定义毒性伤害并探索有毒作用的机制。该项目虽然侧重于药理学和毒理学博士项目，但也包括经过很强的生物或化学培训的学生，他们可能会在导师的家庭部门内参加其他项目。康涅狄格大学的全职教职员工将代表4个学院的8个系和来自私营部门的10名毒物学家担任项目教员。学生将学习毒理学、药理学、病理学、分子生物学和统计学等高级课程的核心课程，以及个性化的选修课。毒理学学生必须通过一系列全面的笔试和口试，并公开为他们的论文研究辩护。研究性培训在项目初期开始，到第三年结束时几乎达到全日制。对于博士后实习生，可能需要进行有限的课程作业，具体取决于背景。所有受训人员将被要求参加研讨会、期刊俱乐部和毒理学学者座谈会，在国家或地区会议上介绍他们的研究，并在毒理学相关期刊上发表文章。