Linking sex-specific adaptation to the evolution of infectious disease

将性别特异性适应与传染病的进化联系起来

• 批准号: FT180100248
• 负责人: A/Prof Matthew Hall
• 金额: $ 51.44万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-11-01 至 2022-11-12
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT180100248
• 关键词: Linking; sex; specific; adaptation; evolution

This project aims to examine how differences in the response of males and females to pathogen attack can influence the evolution of infectious disease. This project expects to generate new knowledge in the area of host-pathogen co-evolution, by integrating approaches from the fields of evolutionary genetics, sexual selection, and epidemiology. Expected outcomes include an enhanced capacity to build interdisciplinary collaborations and development of theory that predicts infection dynamics in any species with separate sexes. This is expected to provide significant benefits, such as improving our knowledge of why the sexes differ and potentially providing new avenues for understanding disease outbreaks and preventing population declines or extinctions.

本项目旨在研究男性和女性对病原体攻击的反应差异如何影响传染病的演变。该项目希望通过整合进化遗传学、性选择和流行病学领域的方法，在宿主-病原体共同进化领域产生新的知识。预期成果包括加强能力，建立跨学科合作和发展理论，预测感染动态在任何物种与不同性别。预计这将带来巨大的好处，例如提高我们对性别差异的认识，并可能为了解疾病爆发和防止人口下降或减少提供新的途径。