MEDICINAL CHEMISTRY-SYNTHESIS OF POTENTIAL TREATMENT

潜在治疗药物的化学合成

• 批准号: 2892671
• 负责人: Peter C Meltzer
• 金额: --
• 依托单位: ORGANIX, INC.
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-29 至 1999-09-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2892671
• 关键词: cocaine; drug addiction antagonist; drug design /synthesis /production

One of the primary program objectives of the National Institute on Drug Abuse (NIDA) is to develop safe and effective medications which will eliminate craving and drug-seeking behavior in cocaine addicts. These drugs should either substitute for cocaine or antagonize its effects. At the present time, there is no safe and effective treatment available to eliminate or alleviate craving and drug-seeking behavior in cocaine addicts. This contract will provide a resource for NIDA to acquire new and innovative compounds for evaluation by MDD as potential treatment agents for cocaine abuse. It will also allow for the scale-up production, as well as production of analogs, of promising compounds resulting from this project and from past projects.

国家研究所的主要方案目标之一是 药物滥用（NIDA）是开发安全有效的药物 这将消除对可卡因的渴望和寻求毒品的行为， 瘾君子 这些药物应该替代可卡因或对抗 它的影响。 目前还没有安全有效的 消除或减轻毒瘾和寻求毒品的治疗 可卡因成瘾者的行为 该合同将提供资源， NIDA将收购新的创新化合物进行评估 MDD作为可卡因滥用的潜在治疗药物。它还将 允许放大生产，以及生产类似物， 从这个项目和过去产生的有前途的化合物 项目