MEDICINAL CHEMISTRY-SYNTHESIS OF POTENTIAL TREATMENT

国家研究所的主要计划目标之一是 药物滥用(NIDA)是为了开发安全有效的药物 它将消除对可卡因的渴望和寻求毒品的行为 瘾君子。这些药物要么可以替代可卡因，要么可以对抗可卡因。 它的影响。目前，还没有安全有效的 可用于消除或缓解渴求和寻求毒品的治疗 可卡因成瘾者的行为。这份合同将为 NIDA将获得新的创新化合物，供 MDD作为可卡因滥用的潜在治疗药物。它还将 考虑到扩大生产，以及生产类似物， 从这个项目和过去得到的有希望的化合物 项目。

One of the primary program objectives of the National Institute on Drug Abuse (NIDA) is to develop safe and effective medications which will eliminate craving and drug-seeking behavior in cocaine addicts. These drugs should either substitute for cocaine or antagonize its effects. At the present time, there is no safe and effective treatment available to eliminate or alleviate craving and drug-seeking behavior in cocaine addicts. This contract will provide a resource for NIDA to acquire new and innovative compounds for evaluation by MDD as potential treatment agents for cocaine abuse. It will also allow for the scale-up production, as well as production of analogs, of promising compounds resulting from this project and from past projects.