EPIDEMIOLOGIC STUDIES IN BREAST AND COLON CANCER CONTROL

描述：(申请人描述)这份预防性申请 肿瘤学学术奖将允许申请者发展为 从事癌症病因学流行病学研究的独立研究员 并在明确的以人群为基础的管理保健环境中进行预防。这 申请由健康中心的教职员工联合赞助 癌症预防研究项目--团体健康合作社的研究 弗雷德·哈钦森癌症研究中心的 华盛顿大学流行病学系。在这个背景下，Dr。 曼德尔森计划继续一个为期四年的项目，该项目包括 活动、研究生教学、高级培训和三项研究 项目。建议的研究项目：1.一项横断面研究 乳腺癌患者乳腺细胞增殖和钼靶密度的研究 乳房切除活检。 2.老年妇女乳腺X光摄影表现的评价。 3.激素替代治疗与腺瘤的病例对照研究 息肉。 该计划侧重于三个具体的感兴趣领域：使用 生物标记物在癌症流行病学研究、癌症筛查评估和 癌症病因学。 该计划的完成将为成功的 独立从事癌症控制研究。

DESCRIPTION: (Applicant's Description) This application for a Preventive Oncology Academic Award will allow the applicant to develop as an independent researcher engaged in epidemiologic studies of cancer etiology and prevention in a defined population-based, managed care setting. This application is jointly sponsored by faculty from the Center for Health Studies at Group Health Cooperative, the Cancer Prevention Research Program of the Fred Hutchinson Cancer Research Center, and the Department of Epidemiology at the University of Washington. In this setting, Dr. Mandelson plans to pursue a four-year program that consists of academic activities, post-graduate teaching, advanced training, and three research projects. Research Projects Proposed: 1. A cross-sectional study of breast cell proliferation and mammographic density in women undergoing excisional breast biopsy. 2. An evaluation of mammography performance in elderly women. 3. A case-control study of hormone replacement therapy and adenomatous polyps. This plan is focused on three specific areas of interest: the use of biomarkers in cancer epidemiology research, cancer screening evaluation, and cancer etiology. Completion of this program will provide a strong foundation for a successful independent career in cancer control research.