EPIDEMIOLOGIC STUDIES IN BREAST AND COLON CANCER CONTROL

描述：（申请人描述）本预防性 肿瘤学学术奖将允许申请人发展为 从事癌症病因学流行病学研究的独立研究人员 和预防在一个确定的人口为基础的，管理式的护理设置。 这 申请是由卫生中心的教师联合赞助的 团体健康合作社的研究，癌症预防研究计划 弗雷德哈钦森癌症研究中心，以及 华盛顿大学的流行病学。 在这种情况下，博士。 曼德尔森计划进行一项为期四年的计划，包括学术 活动，研究生教学，高级培训和三项研究 项目 研究计划：1。 的现况调查 乳腺细胞增殖和乳腺摄影密度 乳房切除活检。 2. 老年妇女乳腺X线摄影性能的评价。 3. 激素替代治疗与乳腺腺瘤性病变的病例对照研究 息肉 该计划侧重于三个具体的利益领域： 癌症流行病学研究中的生物标志物，癌症筛查评估，以及 癌症病因学 该计划的完成将提供一个成功的坚实基础 独立从事癌症控制研究。

DESCRIPTION: (Applicant's Description) This application for a Preventive Oncology Academic Award will allow the applicant to develop as an independent researcher engaged in epidemiologic studies of cancer etiology and prevention in a defined population-based, managed care setting. This application is jointly sponsored by faculty from the Center for Health Studies at Group Health Cooperative, the Cancer Prevention Research Program of the Fred Hutchinson Cancer Research Center, and the Department of Epidemiology at the University of Washington. In this setting, Dr. Mandelson plans to pursue a four-year program that consists of academic activities, post-graduate teaching, advanced training, and three research projects. Research Projects Proposed: 1. A cross-sectional study of breast cell proliferation and mammographic density in women undergoing excisional breast biopsy. 2. An evaluation of mammography performance in elderly women. 3. A case-control study of hormone replacement therapy and adenomatous polyps. This plan is focused on three specific areas of interest: the use of biomarkers in cancer epidemiology research, cancer screening evaluation, and cancer etiology. Completion of this program will provide a strong foundation for a successful independent career in cancer control research.