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ASSESSING DIET CANCER ASSOCIATION IN NATIVE AMERICANS

评估美洲原住民饮食癌症协会

基本信息

批准号：
2895379
负责人：
NICOLETTE I TEUFEL-SHONE
金额：
$ 7.42万
依托单位：
UNIVERSITY OF ARIZONA
依托单位国家：
美国
项目类别：
财政年份：
1995
资助国家：
美国
起止时间：
1995-09-01 至 2001-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/2895379
关键词：
Native Americans computer data analysis computer human interaction computer system design /evaluation handbook human subject information systems nutrient intake activity nutrition aspect of cancer nutrition related tag questionnaires

项目摘要

Accurate assessment of usual dietary intake is critical to understanding the relationship between diet and cancer epidemiology, biology, control and prevention. For Native Americans, such quantitative information is limited. The application of dietary data that does exist for Native Americans to cancer studies is restricted by several factors: (1) most reports are based on short-term intake; (2) cultural differences in portion sizes has not been considered a significant variable; (3) micronutrient intake is not reported; (4) micronutrient content of some seasonally consumed wild foods is unknown; and (5) inter-reservation diet diversity limits the validity of extending results from one population to another. Within some communities, cultural and economic differences in food choices, availability, preparation, processing techniques, appropriate portion sizes, and food classification systems impair the applicability and validity of food frequency questionnaires (FFQs) used in nationwide surveys. The Native American diet is changing and cancer is rapidly becoming a significant health problem for this minority population; incidence and age-adjusted mortality rates of cervical, stomach and gallbladder cancer among Native Americans are two to twenty times higher than that reported for US all races. FFQ-based epidemiologic studies of diet-cancer associations in Native American populations are crippled by the absence of culturally appropriate dietary assessment tools. The goal of this project is to improve our understanding of diet-cancer associations as observed among Native Americans, by developing a dietary assessment technique which allows Native Americans to accurately report their usual food intake. Working with tribes in the Southwest, project aims are (1) to use qualitative (focus groups) and quantitative techniques (multiple 24hr recalls) to develop valid, reliable and culturally competent FFQ templates that can be "culture specific" adapted, (2) to design and test a manual which outlines steps for culturally adapting the FFQ templates, and (3) to develop supportive computer analyses programs to assess nutrient intake relative to cancer risks. These tools promise to improve FFQ-based epidemiologic studies of diet-cancer associations and will assist in the design, implementation, monitoring and evaluation of preventive oncology interventions among Native Americans. This proposal for research will be the major component of a five-year Academic Award. As a faculty member in the UA College of Medicine and the Arizona Graduate Program in Public Health, the investigator will incorporate information and perspectives developed from this experience, into preexisting and newly developed courses and internships for medical and public health students. The investigator will enhance her own education with continued course work in advanced epidemiology, biology of cancer and ethnobotany.

准确评估日常饮食摄入量对于理解至关重要饮食与癌症流行病学、生物学、控制之间的关系和预防。对于美洲原住民来说，此类定量信息是有限的。 Native 确实存在的饮食数据的应用美国人对癌症的研究受到几个因素的限制：（1）大多数报告基于短期摄入量； (2)文化差异份量大小并未被视为重要变量； (3) 未报告微量营养素的摄入量； (4)一些微量营养素含量季节性食用的野生食物未知； (5) 预订间饮食多样性限制了将结果从一个群体扩展到其他。在一些社区内，文化和经济差异食物选择、可用性、准备、加工技术、适当的份量和食品分类系统会损害食物频率问卷（FFQ）的适用性和有效性全国范围内的调查。美洲原住民的饮食正在发生变化，癌症正在迅速成为一种该少数群体存在严重的健康问题；发生率和宫颈癌、胃癌和胆囊癌的年龄调整死亡率美洲原住民的比例比报道的高出两到二十倍对于美国所有种族。基于 FFQ 的饮食癌症流行病学研究美洲原住民中的协会由于缺乏文化上适当的饮食评估工具。该项目的目标是为了提高我们对观察到的饮食与癌症关联的理解在美洲原住民中，通过开发一种饮食评估技术允许美洲原住民准确报告他们平时的食物摄入量。与西南部的部落合作，项目目标是 (1) 使用定性（焦点小组）和定量技术（多个 24 小时召回）以开发有效、可靠且符合文化要求的 FFQ 模板可以根据“特定文化”进行调整，(2) 设计和测试手册其中概述了在文化上适应 FFQ 模板的步骤，以及 (3) 开发支持性计算机分析程序来评估营养摄入量与癌症风险相关。这些工具有望改进基于 FFQ 的饮食与癌症关联的流行病学研究将有助于预防肿瘤学的设计、实施、监测和评估对美洲原住民的干预。该研究提案将成为五年计划的主要组成部分学术奖。作为 UA 医学院和亚利桑那州公共卫生研究生项目，调查员将纳入从这一经验中获得的信息和观点，纳入现有和新开发的医学课程和实习和公共卫生学生。调查员将增强自己的能力继续进行高级流行病学、生物学课程的教育癌症和民族植物学。