RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
批准号:
6186375
负责人:
KEH-MING LIN
金额:
$44.01万
依托单位国家:
美国
项目类别:
财政年份:
1990
资助国家:
美国
项目状态:
已结题
起止时间:
1990-09-01 至 2001-04-30
中文摘要
描述(改编自申请人摘要):该中心是
成立于1990年。其主要使命是弥合
生物学和社会文化研究工作,
建立一个更全面的生物、心理、社会和文化综合体,
精神病学研究和实践的方法。这份更新申请
寻求五年的支持,以继续和扩大该中心的研究
施政纲要的演讲建立在其基础设施的坚实基础上,
在过去五年中开发的研究工具,该中心计划
将先进的研究方法应用于临床和社区
设置,同时评估生物,
精神病发病率、疾病分类学和
治疗反应,并检查这些因素如何相互作用
彼此之间。还将介绍保健服务方法,
允许使用来自现有药物处方的数据
监控系统
本建议书所包括的研究项目包括五项研究
研究领域包括:(1)
最近开发的药物遗传学探针具有多种族/多
患有不同精神疾病的文化患者;(2)
使用磁共振波谱测量大脑中的锂浓度
与锂反应的种族差异有关;(3)
抑郁症的生物心理社会评估,包括横断面和
纵向,在一个多民族的精神卫生保健设置;(4)长期-
社区华裔儿童长期纵向随访研究
ICD-10定义的神经衰弱患者;(5)使用大剂量
药物处方的次要数据集,以研究种族
与其他临床和社会人口统计学变量相互作用,
药物处方的模式。
这种生物医学和社会文化传统的更充分融合将
有助于确保精神病学研究的进展
适当和有效地应用于各种患者
社会文化和种族背景。与此同时,
跨文化的观察和测试将大大有助于
精神病学理论的验证和进一步发展,
实践
英文摘要
DESCRIPTION (Adapted from Applicant's Abstract): The Center was
established in 1990. Its primary mission is to bridge the gap between
biological and sociocultural research efforts and to contribute towards
the establishment of a more fully integrated bio-psycho-socio-cultural
approach to psychiatric research and practice. This renewal application
seeks five years of support to continue and expand the Center's research
agenda. Building upon the solid foundation of its infrastructure and
research tools developed over the past five years, the Center plans to
apply advanced research methodologies into clinical and community
settings, to concurrently assess the influence of biological,
psychosocial and cultural factors in psychiatric morbidity, nosology and
treatment responses, and to examine how these factors might interact
with one another. Also introduced will be health services methodology to
allow the use of data derived from an existing medication prescription
monitoring system.
The research projects included in this proposal include five research
areas examining the following issues: (1) the clinical utility of
recently developed pharmacogenetic probes with multi-ethnic/multi-
cultural patients suffering from different psychiatric conditions; (2)
the use of MR spectroscopy to measure lithium concentration in the brain
in relation to ethnic differences in response to lithium; (3)
biopsychosocial assessment of major depression, both cross-sectional and
longitudinal, in a multi-ethnic mental health care setting; (4) long-
term longitudinal follow-up of a community sample of Chinese-American
patients with ICD-10 defined neurasthenia; and (5) the use of a large
secondary data set of medication prescriptions to study how ethnicity
interacts with other clinical and sociodemographic variables in affecting
the patterns of medication prescription.
This fuller integration of biomedical and sociocultural traditions will
help to ensure that advances in psychiatric research will be
appropriately and effectively applied to patients from diverse
sociocultural and ethnic backgrounds. At the same time, cross-ethnic and
cross-cultural observations and testing will contribute significantly
to the validation and further development of psychiatric theories and
practices.
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DOI:
10.1016/s0193-953x(18)30045-5
发表时间:
1995-09-01
期刊:
PSYCHIATRIC CLINICS OF NORTH AMERICA
影响因子:
1.7
作者:
[LIN, KM, ANDERSON, D, POLAND, RE]
通讯作者:
POLAND, RE
Biological differences in depression and anxiety across races and ethnic groups.
不同种族和族裔群体抑郁和焦虑的生物学差异。
DOI:
--
发表时间:
2001
期刊:
The Journal of clinical psychiatry
影响因子:
--
作者:
[Lin,KM]
通讯作者:
Lin,KM
DOI:
10.1097/00005053-199206000-00008
发表时间:
1992-06-01
期刊:
JOURNAL OF NERVOUS AND MENTAL DISEASE
影响因子:
1.9
作者:
[LIN, KM, LAU, JKC, NAKASAKI, G]
通讯作者:
NAKASAKI, G
Cerebral perfusion and neuropsychological consequences of chronic cocaine use.
长期使用可卡因的脑灌注和神经心理学后果。
DOI:
10.1176/jnp.5.4.419
发表时间:
1993
期刊:
The Journal of neuropsychiatry and clinical neurosciences
影响因子:
--
作者:
[Strickland,TL, Mena,I, Villanueva-Meyer,J, Miller,BL, Cummings,J, Mehringer,CM, Satz,P, Myers,H]
通讯作者:
Myers,H
Comparative study of diagnostic systems: Chinese Classification of Mental Disorders-Second Edition versus DSM-III-R.
诊断系统的比较研究:中国精神障碍分类第二版与DSM-III-R。
DOI:
10.1016/0010-440x(94)90227-5
发表时间:
1994
期刊:
Comprehensive psychiatry
影响因子:
7.3
作者:
[Zheng,YP, Lin,KM, Zhao,JP, Zhang,MY, Yong,D]
通讯作者:
Yong,D
共 11 条
Ethnic Variations in Antidepressant Response
-
批准号:6398110
-
项目类别:
-
资助金额:$42.17万
-
财政年份:2001
-
负责人:KEH-MING LIN
-
依托单位:
Ethnic Variations in Antidepressant Response
-
批准号:6539190
-
项目类别:
-
资助金额:$43.96万
-
财政年份:2001
-
负责人:KEH-MING LIN
-
依托单位:
Ethnic Variations in Antidepressant Response
-
批准号:6639218
-
项目类别:
-
资助金额:$45.13万
-
财政年份:2001
-
负责人:KEH-MING LIN
-
依托单位:
ETHNICITY AND CLINICAL PHARMACOGENETICS
-
批准号:6314410
-
项目类别:
-
资助金额:$11.28万
-
财政年份:2000
-
负责人:KEH-MING LIN
-
依托单位:
INFLUENCE OF ETHNICITY ON BRAIN LITHIUM--7-LI MAGNETIC RESONANCE IMAGING
-
批准号:6314411
-
项目类别:
-
资助金额:$11.28万
-
财政年份:2000
-
负责人:KEH-MING LIN
-
依托单位:
INFLUENCE OF ETHNICITY ON BRAIN LITHIUM--7-LI MAGNETIC RESONANCE IMAGING
-
批准号:6111514
-
项目类别:
-
资助金额:$11.28万
-
财政年份:1999
-
负责人:KEH-MING LIN
-
依托单位:
ETHNICITY AND CLINICAL PHARMACOGENETICS
-
批准号:6111513
-
项目类别:
-
资助金额:$11.28万
-
财政年份:1999
-
负责人:KEH-MING LIN
-
依托单位:
ETHNICITY AND CLINICAL PHARMACOGENETICS
-
批准号:6273465
-
项目类别:
-
资助金额:$15.91万
-
财政年份:1998
-
负责人:KEH-MING LIN
-
依托单位:
INFLUENCE OF ETHNICITY ON BRAIN LITHIUM--7-LI MAGNETIC RESONANCE IMAGING
-
批准号:6273466
-
项目类别:
-
资助金额:$15.91万
-
财政年份:1998
-
负责人:KEH-MING LIN
-
依托单位:
ETHNICITY AND CLINICAL PHARMACOGENETICS
-
批准号:6243123
-
项目类别:
-
资助金额:$17.2万
-
财政年份:1997
-
负责人:KEH-MING LIN
-
依托单位:
INFLUENCE OF ETHNICITY ON BRAIN LITHIUM--7-LI MAGNETIC RESONANCE IMAGING
-
批准号:6243124
-
项目类别:
-
资助金额:$17.2万
-
财政年份:1997
-
负责人:KEH-MING LIN
-
依托单位:
ETHNICITY AND DIFFERENTIAL RESPONSES TO BENZODIAZEPINES
-
批准号:3387193
-
项目类别:
-
资助金额:$16.23万
-
财政年份:1991
-
负责人:KEH-MING LIN
-
依托单位:
ETHNICITY AND DIFFERENTIAL RESPONSES TO BENZODIAZEPINES
-
批准号:3387192
-
项目类别:
-
资助金额:$18.6万
-
财政年份:1991
-
负责人:KEH-MING LIN
-
依托单位:
ETHNICITY AND DIFFERENTIAL RESPONSES TO BENZODIAZEPINES
-
批准号:2247576
-
项目类别:
-
资助金额:$16.18万
-
财政年份:1991
-
负责人:KEH-MING LIN
-
依托单位:
RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
-
批准号:3387013
-
项目类别:
-
资助金额:$76.13万
-
财政年份:1990
-
负责人:KEH-MING LIN
-
依托单位:
RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
-
批准号:2721650
-
项目类别:
-
资助金额:$4.63万
-
财政年份:1990
-
负责人:KEH-MING LIN
-
依托单位:
RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
-
批准号:2415947
-
项目类别:
-
资助金额:$120.37万
-
财政年份:1990
-
负责人:KEH-MING LIN
-
依托单位:
RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
-
批准号:2247470
-
项目类别:
-
资助金额:$96.48万
-
财政年份:1990
-
负责人:KEH-MING LIN
-
依托单位:
RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
-
批准号:2033831
-
项目类别:
-
资助金额:$106.1万
-
财政年份:1990
-
负责人:KEH-MING LIN
-
依托单位:
RESEARCH CENTER ON THE PSYCHOBIOLOGY OF ETHNICITY
-
批准号:2890444
-
项目类别:
-
资助金额:$78.93万
-
财政年份:1990
-
负责人:KEH-MING LIN
-
依托单位:
海外基金