CONFERENCE OF THE INTERNATIONAL PROTEOLYSIS SOCIETY

这是对一个新成立的学会--国际蛋白分解学会--第一次会议的支持请求。成立了一个正式的协会，以促进基础、临床和工业科学家之间的互动，这是因为人们越来越认识到，在从细菌到人类的各种生物体中，蛋白酶及其抑制物在正常和病理过程中扮演着多种角色。国际蛋白分解协会是由一个非正式组织国际蛋白分解委员会发展而来的，它由三个区域委员会组成：美国蛋白分解委员会、欧洲蛋白分解委员会和日本蛋白分解委员会。1973年至1996年，ICOP组织了11次国际科学家会议，他们对细胞内蛋白质分解和蛋白质周转有研究兴趣。上一次在美国举行的ICOP会议是1992年在弗吉尼亚州威廉斯堡举行的HELP会议，由共同的PIS之一(J.Bond)和PI(B.Sloane)组织。国际蛋白质分解学会的目标是组织对这一主题领域有共同兴趣的科学家的国际会议，为传播最新研究提供一个论坛，促进合作，并作为关于蛋白酶及其抑制剂的会议的信息中心。大约30名与会者将是国际公认的专家，他们将进行平台演讲。因为该协会的一个主要目标是鼓励根据提交的摘要选出的年轻科学家。预计其余与会者(约350人)将以海报的形式介绍他们的工作。本文将就蛋白水解酶及其抑制剂的结构、作用机制、调节、生物学和病理功能等方面的最新进展进行讨论。会议将为自由讨论这一领域知识前沿的数据和概念提供一个激动人心的学术环境。我们预计这次会议将有来自学术界和工业界不同专业的基础、临床和应用研究人员参加。第一届国际蛋白质分解学会会议的成功将取决于组织者是否有能力吸引从事该领域前沿研究的优秀演讲者，并为他们的旅行、住宿和注册费用提供资金。

This is a request for support for the first meeting of a newly organized society, the International Proteolysis Society. A formal society was formed to facilitate interactions among basic, clinical and industry scientists resulting from an increased awareness of the multiple roles played by proteases and their inhibitors in normal and pathological processes in organisms ranging from bacteria to humans. The International Proteolysis Society evolved from an informal organization, the International Committee on Proteolysis or ICOP which was comprised of three regional committees: the American Committee on Proteolysis, the European Committee on Proteolysis and the Japanese committee on Proteolysis. ICOP organized eleven international conferences of scientists with research interests in intracellular proteolysis and protein turnover from 1973-1996. The last ICOP meeting in the USA was help in Williamsburg, VA in 1992 and organized by one of the co-PIs (J.Bond) and the PI (B. Sloane). The objectives of the International Proteolysis Society are to organize international meetings of scientists who share an interest in the subject area, to provide a forum for dissemination of the latest research, to facilitate collaborations, and to serve as a clearing house for meetings on proteases and their inhibitors. About 30 of the conferees will be internationally recognized experts who will give platform presentations. Since a major goal of the society is to encourage younger scientists who are chosen on the basis of submitted abstracts. It is expected that the remainder of the attendees (approximately 350) will give poster presentations of their work. Recent advances in elucidating the structures, mechanisms, regulation, and biological and pathological functions of proteolytic enzymes and their inhibitors will be discussed. The conference will provide a stimulating academic environment for free-flowing discussion of data and concepts at the frontiers of knowledge in this field. We anticipate that this conference will be attended by basic, clinical and applied investigators from a wide variety of specialities in academia and industry. The success of the first International Proteolysis Society meeting will depend on the organizers' ability to attract excellent speakers doing the research on the leading edge of the field and to fund their travel, hotel and registration costs.