REMODELING RESEARCH ANIMAL ROOMS

改造研究动物室

• 批准号: 3059058
• 负责人: DONALD H MAUL
• 金额: $ 20.74万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-08-01 至 1992-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3059058
• 关键词: animal care; animal colony; building /facility design /renovation; controlled environment

The specific aim of this animal resource improvement proposal is to continue the University's progress toward AAALAC accreditation. The University is 80-85% complete in renovation of all lab animal facilities but some are outdated and must be improved. The research animal facility and the quarantine facility at the Veterinary Teaching Hospital (VTH) currently house cats and/or dogs in projects from the departments of Radiology and Radiation Biology, and Clinical Sciences in the College of Veterinary Medicine and Biomedical Sciences totaling $1.84 million of annual research and teaching grants. However, the CSU Animal Care and Use Committee and the USDA has cited the research animal facilities as inadequate with regard to cage size, species, and source separation capabilities, and physical plant defects. Cats on quarantine must now be housed together with newly arrived random source cats in the VTH since the quarantine facility lacks space to house cats. This makes it impossible to meet the requirements of the "Guide" for animal source and health status separation. For dogs, the individual cages cannot be properly cleaned and runs are too small to house large dogs in pairs. With the pending USDA requirements for larger cage size and socialization, these runs will undoubtedly be too small. In the quarantine facility one room has no HVAC system and cannot be used for animals now but could be used for cats. This proposal has the following specific aims for renovation of the VTH research animal and quarantine facilities. Specific Aim # 1: To renovate the VTH research animal facilities to provide; 1) regraded and trenched floors to allow efficient cleaning of dog runs, 2) replacement of dog cages and runs with stainless steel cages and elevated floor runs with versatility to adapt to larger cage size requirements or other species such as swine or ruminants, 3) two rooms to house conditioned cats, 4) solid ceilings, 5) epoxy floor, wall and ceiling covering, and 6) relocation of office space. Specific Aims #2: To renovate room 101 of the quarantine facility to allow quarantine and conditioning cats by providing; 1) an HVAC system, 2) four cubicle rooms for isolation and quarantine of cats, 3) solid ceiling, 4) epoxy floor, wall and ceiling coverings, and 5) a room with a dishwasher capable of supplying 180oF water to disinfect food and water bowls used in this facility, 6) new 4 sq. ft. cat cages for the cubicles.

这项动物资源改善建议的具体目标是 继续大学的AAALAC认证的进展。 的 大学所有实验室动物设施的翻新完成了80-85% 但有些已经过时，必须加以改进。 研究动物设施 以及兽医教学医院的检疫设施 目前，猫和/或狗的住房项目， 放射学与放射生物学及临床科学 兽医和生物医学科学总计184万美元， 年度研究和教学赠款。 CSU动物护理和使用 委员会和美国农业部引用了研究动物设施， 笼的大小、物种和源分离方面的不足 能力和物理工厂缺陷。 被隔离的猫现在必须 与新来的随机来源猫一起安置在VTH， 检疫设施缺乏收容猫只的空间。 这使得不可能 符合《指南》对动物来源和健康状况的要求 分居 对于狗来说，单独的笼子不能被适当地清洁， 跑道太小，不能让大型犬成对地居住。 随着美国农业部 对于更大的笼子尺寸和社会化的要求，这些运行将 无疑是太小了。 在隔离设施中，有一个房间没有空调， 现在不能用于动物，但可以用于猫。 这 该方案对VTH研究的革新有以下具体目标 动物检疫设施。 具体目标#1：翻新VTH研究动物设施， 提供; 1）重新分级和沟槽地板，以有效清洁狗 2）更换狗笼和不锈钢笼， 高架地板运行，具有多功能性，以适应更大的笼子尺寸 要求或其他物种，如猪或反刍动物，3）两个房间， 房屋空调猫，4）固体天花板，5）环氧树脂地板，墙壁和天花板 （六）办公场所搬迁。 具体目标#2：改造隔离设施的101室， 检疫和空调猫提供; 1）暖通空调系统，2）四个 隔离和检疫猫的小房间，3）实心天花板，4） 环氧树脂地板，墙壁和天花板覆盖物，以及5）带洗碗机的房间 能够提供180 oF的水来消毒食物和水碗， 这个设施，6）新的4平方米。英尺猫笼是用来装猫的