EQUIPMENT REQUEST

这项动物资源改良提案的目的是让 大学将继续朝着AAALAC认证取得进展 在美国国立卫生研究院最近提供的两笔翻修赠款的帮助下，该项目进展顺利。 这项提案涉及我们计划中的下一个项目 我知道了。 位于生理学大楼的外科套房对于 每年为绵羊和小牛做500次手术。外科手术 套房足以进行无菌手术，然而，笔在 恢复室需要大修，因为他们有剥落的油漆和 生锈了。地板是木板条，直接放在密封的 混凝土地板，这样就可以清理板条之间和下面的粪便， 在保持动物清洁和干燥的同时，很难做到。《木头》 地板不能在密封状态下维护，因此也不能 不透湿，不能充分清洁和消毒。 这些围栏必须更换，以便有足够的卫生条件，提高动物的 舒适和健康，并使清洁更有效率。 两年前，我们开始为调查人员提供病毒和 无支原体抗体的啮齿动物。这一点已被我们的 科学家和我们在维持VAF方面取得了相对成功的成果 成群的老鼠和老鼠。然而，我们偶尔也会有休息时间 遏制。我们没有可提供的笼子设备 笼间隔离，限制传染病的传播。 我们必须升级到隔离器笼子系统，才能提供所需的 保持无病啮齿动物所需的质量控制水平。这 该提案有以下具体目标。 具体目标#一：购买加高地板的不锈钢笔 由乙烯基涂层扩展金属制成，以取代现有的钢笔 用于抱羊或小牛以供手术后恢复的生理楼 和短期的手术后实验。 具体目标2：收购Thoren Cage Systems，Inc. 独立通风保持架和保持架与层流 换站以提升我们长期储存病毒的能力 和无霉斑抗体的啮齿动物。

The intent of this animal resource improvement proposal is to allow the University to oontinue progress toward AAALAC accreditation which is progressing well with the help of two recent renovation grants from NIH. This proposal addresses the next project in our plan to become aocredited. A surgical suite located in the Physiology building is essential for performing 500 surgeries per year on sheep and calves. The surgical suite is adequate to perform aseptic surgery, however, the pens in the recovery room need major repairs since they have peeling paint and are rusting. The floors are wooden slats lying directly on the sealed concrete floor so cleaning feces from between and beneath the slats, while keeping the animals clean and dry, is difficult. The wooden floors cannot be maintained in a sealed condition and so are not impervious to moisture and cannot be cleaned and sanitized adequately. These pens must be replaced to allow adequate sanitation, enhance animal comfort and health, and make cleaning more efficient. Two years ago we began a service to provide investigators with viral and mycoplasmal antibody free rodents. This has been well accepted by our scientists and we have been relatively successful in maintaining VAF colonies of rats and mice. However, we have had ocasional breaks in containment. We do not have the caging equipment to provide cage-to-cage isolation which limits the spread of infectious diseases. We must upgrade to an isolator caging system to give us the required level of quality control needed to maintain disease free rodents. This proposal has the following specific aims. Specific Aim #I: To purchasing stainless steel pens with elevated floors made of vinyl coated expanded metal to replace existing pens in the Physiology building to hold sheep or calves for post surgery recovery and short term post surgical experiments. Specific Aim #2: To purchase Thoren Caging Systems, Inc. positive individually ventilated caging system racks and cages and laminar flow change stations to upgrade our ability for long term housing of viral and mycoplamsal antibody free rodents.