REMODELING AN ANIMAL FACILITY IN SURGICAL METABOLIC LAB

改造外科代谢实验室的动物设施

• 批准号: 3451176
• 负责人: DONALD H MAUL
• 金额: $ 26.08万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-04-19 至 1992-04-01
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3451176
• 关键词: Rodentias; animal care; animal colony; biomedical equipment purchase; building /facility design /renovation; cow; dogs; laboratory rabbit; sheep; surgery

The specific aim of this animal resources improvement proposal is to continue the University's progress toward laboratory animal care centralization and attaining AAALAC accreditation. The University is 75-80% complete in renovation of all its lab animal facilities. Facilities on the main campus have been centralized or completely renovated but some facilities on other parts of the campus are outdated and must be upgraded to meet the above goals. The "Foxhound" building in the surgical/metabolic laboratory on the foothills campus currently houses laboratory animals used by the departments of Physiology, Radiation Biology, and Pathology. Sheep, calves, dogs, rabbits and rodents are used extensively by investigators in these departments and require quality indoor housing. The research done in the Foxhound building totals more than $2.8 million of annual research and teaching grants from NIH, USDA, EPA and the State of Colorado. The centralized animal facilities on the main campus were not designed to house the larger species listed and the current facilities on the foothills campus do not meet the environmental standards outlined in the Guide for the Care and Use of Laboratory Animals and therefore are inadequate for AAALAC accreditation. This proposal has the following specific aims for renovation of the Foxhound facility. SPECIFIC AIM #1: To renovate the Foxhound building on the foothills campus to provide 1) an upgraded air handling system with air conditioning and elimination of 50-100% air recirculation, 2) solid ceilings, 3) re-grading the floors in two rooms to allow efficient cleaning of runs for small ruminants or dogs, and 4) epoxy covering for the floors, walls and ceilings, and 5) renovate one room by building five cubicles, each to house different small animal species or investigator's projects. SPECIFIC AIM #2: To provide equipment as follows; 1) purchase stainless steel runs with the versatility to house small ruminants, dogs, or swine in two rooms, 2) equip one room with stainless steel cages for rabbits, and 3) purchase racks and rodent cages to house rodents in cubicles.

本动物资源改善建议的具体目的是 继续大学在实验动物护理方面的进展 集中化和获得AAALAC认证。 大学 其所有实验室动物设施的翻新工作已完成75-80%。 主校区的设施已经集中或完全 翻新，但校园其他部分的一些设施， 已经过时，必须升级以实现上述目标。 的 “猎狐犬”大楼位于 山麓校园目前的房屋实验室动物使用的 生理学、放射生物学和病理学系。 绵羊、小牛、狗、兔子和啮齿动物被广泛使用， 调查人员在这些部门，并要求质量室内 住房 在猎狐犬大楼里做的研究 美国国立卫生研究院每年提供超过280万美元的研究和教学赠款， 美国农业部，环保署和科罗拉多州。 中央集权的动物 主校区的设施并不是为了容纳更大的学生而设计的。 所列的物种和山麓校园目前的设施 不符合《指南》中概述的环境标准， 实验动物的护理和使用，因此不充分 获得AAALAC认证。 该提案有以下具体内容 旨在翻新猎狐犬基地 具体目标#1：翻新Foxhound大楼， 山麓校园提供1）升级的空气处理系统， 空调和消除50-100%的空气再循环，2） 实心天花板，3）重新分级两个房间的地板， 有效清洁小型反刍动物或狗的跑道，以及4） 环氧树脂覆盖地板，墙壁和天花板，5）翻新 一间房由五间小房子组成，每一间房子都有不同的大小 动物物种或研究者的项目。 具体目标#2：提供以下设备：1）购买 不锈钢具有多功能性，可容纳小型反刍动物， 狗，或猪在两个房间，2）装备一个房间与不锈钢 笼子的兔子，和3）购买机架和啮齿动物笼的房子 穿牛仔裤的啮齿动物