SENSORY IMPAIRMENT AND FUNCTION IN THE ELDERLY

老年人的感觉障碍和功能

• 批准号: 3078469
• 负责人: RICHARD F UHLMANN
• 金额: $ 5.72万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-02-01 至 1990-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3078469
• 关键词: Alzheimer's disease; cognition; deafness; health behavior; human old age (65+); human subject; psychological tests; questionnaires; satisfaction

Deafness is present in a large proportion of the elderly and has been hypothesized as a risk factor for dementia. Previous studies which explored this hypothesis contain serious methodologic flaws and produced conflicting results. Case-control and cross-sectional studies of deafness as a risk factor for cognitive dysfunction in Senile Dementia of the Alzheimer's Type (SDAT) will be performed. Cases are 50 SDAT patients and controls are 50 patients without dementia at Univ. of Washington clinics. Subjects will be interviewed to obtain historical data. They will also undergo a standardized mental status evaluation and extensive audiologic, and otologic evaluations. Data will be analyzed to determine if an increased prevalence of deafness exists in cases vs. controls as well as to determine the relationship of severity of hearing loss and dementia among SDAT patients. Significant independent associations may have important implications for the prevention and management of dementia. Quality of life factors are frequently considered in geriatric medicine decisions. This study will compare physician, geriatric patient, and spouse (who is often surrogate decision maker for incompetent patient) attitudes about quality of life in a geriatric medicine context. Questionnaires will be administered to approximately 90 academic, community, and nursing home physicians of outpatient geriatric care, 350 geriatric patients and 130 of their spouses. For each patient, respondents will describe medical events in the preceding year which affected the patient's quality of life, assess the overall quality of the patient's life and selected components of it, and complete simulated case management problems concerning values and actions attributable to quality of life assessments. This study will provide basic knowledge with clinical and policy implications about quality of life in elderly patients. In addition to research responsibilities, the principal investigator will direct the Harborview Medical Center inpatient SeniorCare program and have teaching responsibilities for medical students, house officers and fellows.

很大一部分老年人患有耳聋，并且已经 被认为是痴呆症的危险因素。 以前的研究表明 探索了这个包含严重方法论缺陷的假设并产生了 相互矛盾的结果。 耳聋的病例对照和横断面研究 老年痴呆症认知功能障碍的危险因素 将进行阿尔茨海默病类型 (SDAT)。 病例为 50 名 SDAT 患者， 对照是大学的 50 名没有痴呆症的患者。华盛顿诊所。 将对受试者进行访谈以获得历史数据。 他们还将 接受标准化的精神状态评估和广泛的听力学检查， 和耳科评估。 将分析数据以确定是否 与对照相比，病例中耳聋患病率有所增加，并且 确定听力损失严重程度与痴呆症之间的关系 SDAT 患者。 重要的独立协会可能具有重要意义 对预防和管理痴呆症的影响。 老年医学经常考虑生活质量因素 决定。 这项研究将比较医生、老年患者和 配偶（通常是无能力患者的代理决策者） 老年医学背景下对生活质量的态度。 将对大约 90 名学者、 门诊老年护理的社区和疗养院医生，350 老年患者及其 130 名配偶。 对于每位患者，受访者 将描述上一年影响的医疗事件 患者的生活质量，评估患者的整体生活质量 并选定其组成部分，完成模拟案例管理 与生活质量相关的价值观和行为问题 评估。 本研究将提供临床和 政策对老年患者生活质量的影响。 除了研究职责外，首席研究员还将 指导 Harborview 医疗中心住院老年护理计划并拥有 医学生、院舍官员和研究员的教学职责。