Multiscale modelling and nondeterministic optimisation for reliable stents

可靠支架的多尺度建模和非确定性优化

• 批准号: DP180104200
• 负责人: Prof Qing Li
• 金额: $ 31.73万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-06-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180104200
• 关键词: Multiscale; modelling; nondeterministic; optimisation; reliable

This project aims to study modelling and optimisation for a more reliable design of intravascular stents. Intravascular stents are a class of lifelong micro-devices to support blood vessel for restoring circulation. Despite its remarkable initial outcome, the high rate of long-term mechanical failure remains a major concern. This project will tackle plasticity, fatigue damage and fracture across different length scales. The proposed optimisation is expected to minimise failure, thereby enhancing the longevity and reliability of stent therapy. This will have significant benefits, such as accommodating variations in stents and service conditions for achieving a long-lasting and reliable therapeutical outcome.

该项目旨在研究建模和优化，以获得更可靠的血管内支架设计。血管内支架是一类支持血管恢复循环的终身微型装置。尽管其最初的结果令人瞩目，但长期机械故障的高发生率仍然是一个主要问题。该项目将解决不同长度尺度的塑性、疲劳损伤和断裂问题。预期所提出的优化将最大限度地减少失败，从而提高支架治疗的寿命和可靠性。这将具有显著的益处，例如适应支架和服务条件的变化，以实现持久和可靠的治疗结果。