Cereals and rusts: molecular interactions for plant defence, food security

谷物和锈病：植物防御、粮食安全的分子相互作用

• 批准号: DP180103377
• 负责人: Prof Robert Park
• 金额: $ 34.02万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180103377
• 关键词: Cereals; rusts; molecular; interactions; plant

This project aims to discover the fundamental molecular interactions between proteases and protease inhibitors that occur in the ongoing conflict between cereals and their rust fungal pathogens. The research combines plant pathology, genomics and functional proteomics, and is enabled by a rapidly developing experimental approach known as activity-based protein profiling. The knowledge and outcomes potentially benefit plant breeders through significantly improved resistance of cereals to rust diseases in Australia and overseas, thereby enhancing global food security.

该项目旨在发现在谷物和其锈菌病原体之间持续冲突中发生的蛋白水解酶和蛋白水解酶抑制剂之间的基本分子相互作用。这项研究结合了植物病理学、基因组学和功能蛋白质组学，并得到了一种名为基于活性的蛋白质图谱的快速发展的实验方法的支持。这些知识和成果可能使植物育种者受益，因为它显著提高了澳大利亚和海外谷物对锈病的抵抗力，从而加强了全球粮食安全。