DIABETES AND ENDOCRINOLOGY RESEARCH CENTER
DIABETES AND ENDOCRINOLOGY RESEARCH CENTER
批准号:
3102007
负责人:
ANTONIO M GOTTO
金额:
$59.5万
依托单位国家:
美国
项目类别:
财政年份:
1981
资助国家:
美国
项目状态:
已结题
起止时间:
1981-09-30 至 1992-11-30
中文摘要
贝勒医学院建议建立一个糖尿病和
内分泌学研究中心协调和扩大其正在进行的
关于病因和治疗的基础和临床研究计划
糖尿病及其并发症和相关内分泌学的研究进展
条件。虽然已经有相当多的糖尿病相关研究活动
存在,激素放射免疫分析核心设施的建立,
分子内分泌学和组织培养将促进
调查人员之间的跨学科互动,并提高效率
而且性价比高。中心的存在和可获得性
这样的核心将为年轻的调查人员提供一个成为
参与糖尿病相关研究,并积累足够的数据
作为独立研究支持的基础。的资源
该中心还将促进吸引来自
其他领域与糖尿病相关的研究。除了核心之外
设施、一系列新举措以及试点和可行性项目
都被提出了。这些提案将调查基本问题
与糖尿病及其并发症的病因和性质有关
以及与糖尿病患者管理有关的方面。
基础和临床研究的整合和持续评估
中心的有效性将通过建立来实现
跨学科研讨会,介绍正在进行的研究和
内部和外部咨询委员会的定期审查。
英文摘要
Baylor College of Medicine proposes to establish a Diabetes and
Endocrinology Research Center to coordinate and expand its ongoing
programs of basic and clinical research concerning the cause and treatment
of diabetes mellitus, its complications and related endocrinologic
conditions. While considerable diabetes-related research activity already
exists, the establishment of core facilities for hormone radioimmunoassay,
molecular endocrinology and tissue culture will foster enhanced
interdisciplinary interaction among investigators and be more efficient
and cost-effective. The presence of the center and the availability of
such cores will provide an opportunity for young investigators to become
involved in diabetes-related research and accumulate sufficient data to
serve as a basis for independent research support. The resources of the
center will also facilitate attraction of established investigators from
other areas into research related to diabetes. In addition to the core
facilities, a series of new initiatives and pilot and feasibility projects
are proposed. These proposals will investigate fundamental questions
related to the cause and nature of diabetes mellitus and its complications
as well as aspects concerned with the management of diabetic patients.
The integration of basic and clinical research and continuing evaluation
of the effectiveness of the center will be accomplished by establishment
of interdisciplinary seminars, presentation of ongoing research and
periodic reviews by both the Internal and External Advisory Committees.
期刊论文(13)
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Comparison of effects of thyrotropin, phorbol esters, norepinephrine, and carbachol on iodide organification in dog thyroid slices, follicles, and cultured cells.
比较促甲状腺素、佛波酯、去甲肾上腺素和卡巴胆碱对狗甲状腺切片、滤泡和培养细胞中碘化物组织的影响。
DOI:
10.1210/endo-122-5-1915
发表时间:
1988
期刊:
Endocrinology
影响因子:
4.8
作者:
[Rani,CS, Field,JB]
通讯作者:
Field,JB
Structure and chromosomal localization of the human antidiuretic hormone receptor gene.
人类抗利尿激素受体基因的结构和染色体定位。
DOI:
--
发表时间:
1992
期刊:
American journal of human genetics
影响因子:
9.8
作者:
[Seibold,A, Brabet,P, Rosenthal,W, Birnbaumer,M]
通讯作者:
Birnbaumer,M
Beta-adrenergic stimulation contributes to incretin effect in conscious dogs.
β-肾上腺素能刺激有助于清醒狗的肠促胰素作用。
DOI:
10.1152/ajpendo.1991.261.1.e58
发表时间:
1991
期刊:
The American journal of physiology
影响因子:
--
作者:
[Chap,Z, Okuda,Y, Pena,J, Field,JB]
通讯作者:
Field,JB
Hepatic extraction of somatostatin in conscious dogs.
在清醒的狗中通过肝脏提取生长抑素。
DOI:
10.1152/ajpendo.1988.254.2.e214
发表时间:
1988
期刊:
The American journal of physiology
影响因子:
--
作者:
[Chap,Z, Ishida,T, Jones,RH, Pena,JR, Vinik,A, Field,JB]
通讯作者:
Field,JB
Multiple isoforms of ADP-ribosylated G-like proteins from mammalian thyroid membranes.
来自哺乳动物甲状腺膜的 ADP 核糖基化 G 样蛋白的多种亚型。
DOI:
10.1016/s0006-291x(87)80542-9
发表时间:
1987
期刊:
Biochemical and biophysical research communications
影响因子:
3.1
作者:
[Deery,WJ, Rebeiro-Neto,F, Field,JB]
通讯作者:
Field,JB
共 11 条
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION
-
批准号:2286784
-
项目类别:
-
资助金额:$135.0万
-
财政年份:1995
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:6453610
-
项目类别:
-
资助金额:$287.24万
-
财政年份:1989
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:6614434
-
项目类别:
-
资助金额:$360.19万
-
财政年份:1989
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:2722810
-
项目类别:
-
资助金额:$305.56万
-
财政年份:1989
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:6315603
-
项目类别:
-
资助金额:$270.09万
-
财政年份:1989
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:6078266
-
项目类别:
-
资助金额:$256.73万
-
财政年份:1989
-
负责人:ANTONIO M GOTTO
-
依托单位:
SPECIALIZED CENTER OF RESEARCH IN ARTERIOSCLEROSIS
-
批准号:3106633
-
项目类别:
-
资助金额:$197.84万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
NATIONAL RESEARCH AND DEMONSTRATION CTR. - ARTERIOSCLERO
-
批准号:3108493
-
项目类别:
-
资助金额:$267.68万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
A/S SCOR STRUCTURE AND METABOLISM OF PLASMA LIPOPROTEINS
-
批准号:3106632
-
项目类别:
-
资助金额:$188.57万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
DIABETES AND ENDOCRINOLOGY RESEARCH CENTER
-
批准号:3102002
-
项目类别:
-
资助金额:$30.0万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
NATIONAL RESEARCH AND DEMONSTRATION CTR. - ARTERIOSCLERO
-
批准号:3108496
-
项目类别:
-
资助金额:$316.69万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
SPECIALIZED CENTER OF RESEARCH IN ARTERIOSCLEROSIS
-
批准号:3106631
-
项目类别:
-
资助金额:$212.7万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
SCOR IN ARTERIOSCLEROSIS
-
批准号:2216127
-
项目类别:
-
资助金额:$214.03万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
NATIONAL RESEARCH AND DEMONSTRATION CTR. - ARTERIOSCLERO
-
批准号:3108492
-
项目类别:
-
资助金额:$278.85万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
NATIONAL RESEARCH/DEMONSTRATION CENTER--ARTERIOSCLEROSIS
-
批准号:3108495
-
项目类别:
-
资助金额:$266.99万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
SCOR IN ARTERIOSCLEROSIS
-
批准号:2216128
-
项目类别:
-
资助金额:$187.92万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
NATIONAL RESEARCH/DEMONSTRATION CENTER--ARTERIOSCLEROSIS
-
批准号:3108494
-
项目类别:
-
资助金额:$294.35万
-
财政年份:1981
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:6479180
-
项目类别:
-
资助金额:$458.92万
-
财政年份:1977
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:6680649
-
项目类别:
-
资助金额:$10.01万
-
财政年份:1977
-
负责人:ANTONIO M GOTTO
-
依托单位:
GENERAL CLINICAL RESEARCH CENTER
-
批准号:6315558
-
项目类别:
-
资助金额:$338.86万
-
财政年份:1977
-
负责人:ANTONIO M GOTTO
-
依托单位:
海外基金