CLAUDE D PEPPER OLDER AMERICANS INDEPENDENCE CENTER

克劳德·D·佩珀美国老年人独立中心

• 批准号: 3108078
• 负责人: WILLIAM R HAZZARD
• 金额: $ 142.77万
• 依托单位: WAKE FOREST UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 1996-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3108078
• 关键词: aging; clinical trials; hypertension; osteoarthritis; osteoporosis

The bi-institutional Claude D. Pepper Older Americans Independence Center (OAIC) of Bowman Gray School of Medicine of Wake Forest University (BGSM/WFU) and the University of Tennessee-Memphis (UTM) will build upon a tradition of collaborative between the lead investigators at these academic medical centers in the prevention and management of major aging-related chronic diseases and syndromes that jeopardize function as well as longevity in older persons. The administrative and coordinating centers will be based at BGSM/WFU but all of the following activities will take place at both institutions. Specific projects include: 1. One formal intervention study: Therapeutic Exercise for Knee Osteoarthritis 2. Two intervention development studies: a. Osteoporosis: Pharmacologic and Non-pharmacologic interventions b. Trial of Non-Pharmacologic Interventions for Mild Systolic Hypertension in the Elderly (TONE) 3. Research development core: supporting two junior faculty physician investigators who will participate in these intervention trials and two one-year intervention-related pilot studies 4. Three Research Resource Cores a.Recruitment (and recruitment research) b.Biostatistics c.Health quality of life/cost effectiveness 5. Demonstration and Dissemination Core 6. Leadership/Administrative Core These initiatives will build upon strong commitments and investments in developing research faculty and programs in gerontology and geriatrics and the public health sciences at both institutions. Evidence of these commitments and investments include incorporation of a formal course in gerontology and geriatrics in the required undergraduate medical curriculum at BGSM/WFU, required rotations in geriatrics in residences in internal medicine and family medicine at BGSM/WFU, accredited, well-subscribed, and productive geriatric fellowship training programs at both institutions, and a well-developed junior faculty development program at BGSM/WFU. The proposed Pepper OAIC will be fully integrated into these programs consistent with the philosophical basis of program development in gerontology and geriatrics at BGSM/WFU: to imbed these disciplines in the institutional DNA, at it were, to assure their quality, stability and longevity.

双机构克劳德·D·佩珀美国老年人独立中心 维克森林大学鲍曼格雷医学院 (OAIC) （BGSM/WFU）和田纳西大学孟菲斯分校（UTM）将建立在 这些学术界主要研究人员之间合作的传统 医疗中心在预防和管理重大老龄相关疾病方面的作用 危害功能和功能的慢性疾病和综合症 老年人的长寿。 行政和协调中心 将以 BGSM/WFU 为基地，但以下所有活动都将进行 在两个机构都占有一席之地。 具体项目包括： 1. 一项正式的干预研究：膝关节治疗运动 骨关节炎 2. 两项干预发展研究： 一个。骨质疏松症：药物和非药物干预 b.轻度收缩期高血压的非药物干预试验 老年人 (TONE) 3. 研发核心：支持初级师资医师2名 将参加这些干预试验的研究人员和两名 为期一年的干预相关试点研究 4. 三大研究资源核心 a.招聘（和招聘研究） b.生物统计学 c.健康生活质量/成本效益 5、示范传播核心 6. 领导/行政核心 这些举措将建立在对以下方面的坚定承诺和投资的基础上： 发展老年学和老年病学方面的研究人员和项目，以及 两个机构的公共卫生科学。 这些证据 承诺和投资包括将正式课程纳入 本科医学必修课程中的老年学和老年病学 在 BGSM/WFU，需要在内部住宅中进行老年病学轮换 BGSM/WFU 的医学和家庭医学，经过认可、订阅良好，并且 两个机构的富有成效的老年研究金培训计划，以及 BGSM/WFU 制定了完善的初级教师发展计划。 这 拟议的 Pepper OAIC 将完全整合到这些计划中 符合程序开发的哲学基础 BGSM/WFU 的老年学和老年病学：将这些学科融入到 机构DNA，可以说是为了确保其质量、稳定性和 长寿。