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ULTRASTRUCTURE AND FUNCTION OF NERVE AND MUSCLE

ULTRASTRUCTURE AND FUNCTION OF NERVE AND MUSCLE
神经和肌肉的超微结构和功能
批准号：
3116891
负责人：
YASUKO NAKAJIMA
金额：
$15.69万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1988
资助国家：
美国
项目状态：
已结题
起止时间：
1988-03-01 至 1990-08-31
来源：
https://reporter.nih.gov/project-details/3116891
关键词：
Crustacea acetylcholine electron microscopy electrophysiology embryo /fetus freeze etching fresh water environment histochemistry /cytochemistry membrane proteins neural information processing neuroanatomy neuromuscular junction neuromuscular transmission neurophysiology nicotinic receptors stretch receptors synapses tissue /cell culture

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中文摘要
翻译
该项目的目的之一是研究的超微结构
英文摘要
One of the objectives of this project is to investigate the ultrastructure of the crustacean stretch receptor organ in relation to its function. We plan to investigate stretch-induced structural changes in the dendrities of the sensory neuron, where the generator potential occurs, by using ultraquick freezing and freeze-substitution methods. In addition, the membrane fine structure of the inhibitory synapses on the receptor neuron will be studied by using the freeze-fracture method. The other objective of this project is to investigate the ultrastructural and electrophysiological properties of newly-formed neuromuscular junctions in tissue culture. Also we will study the development of extrajunctional acetylcholine receptors in cultured muscle cells by using microelectrophysiological and freeze-fracture methods.
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