课题基金 / 基金详情

MAINTENANCE OF A HISTOCOMPATIBILITY MUTANT MOUSE COLONY

MAINTENANCE OF A HISTOCOMPATIBILITY MUTANT MOUSE COLONY
组织相容性突变小鼠群体的维持
批准号：
3126893
负责人：
ROGER W MELVOLD
金额：
$7.03万
依托单位：
NORTHWESTERN UNIVERSITY AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1979
资助国家：
美国
项目状态：
已结题
起止时间：
1979-09-01 至 1992-08-31
来源：
https://reporter.nih.gov/project-details/3126893
关键词：
animal colony genetic manipulation genetic mapping genetic strain histocompatibility gene histocompatibility typing laboratory mouse major histocompatibility complex mutant serology /serodiagnosis skin transplantation

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中文摘要
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英文摘要
This project proposes to maintain a colony of mice bearing histocompatibility gene mutations, particular those of the H-2 complex, as a resource colony. Incipient mutant strains, currently under development, will be completed and added to the collection. Strains maintained will be systematically monitored to maintain their genetic integrity, by skin grafting and by serological typing. No further large scale screening by skin grafting, for new mutants will be carried out as part of this project. however, additional future mutants may be added as recovered from another separately funded project in which skin grafting is used to monitor the genetic integrity of the NCI mouse colonies.
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ISO-ANTIGENIC TYPING OF MOUSE STRAINS
ISO-ANTIGENIC TYPING OF MOUSE STRAINS
ISO-ANTIGENIC TYPING OF MOUSE STRAINS
PRODUCTION AND MAINTENANCE OF H-2 MUTATIONS
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