Biochemical Engineering MSc

生物化学工程理学硕士

• 批准号: BB/H020632/1
• 负责人: Gary Lye
• 金额: $ 47.25万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Training Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FH020632%2F1
• 关键词: Biochemical; Engineering; MSc

The objective of the UCL Biochemical Engineering MSc is to better enable UK companies to capture the added value associated with knowledge-intensive, high-technology (bio)manufacture. We specifically address practical bioprocess skills needs identified in recent BIGT, ABPI and IB-IGT reports and highlight new opportunities and bioprocess challenges in Industrial Biotechnology and cost-effective global healthcare provision. The existing course has a proven track record of providing high quality interdisciplinary postgraduate education. The new MSc programme will build on this to offer two streams, one for bioscience or chemistry graduates and the other for engineering graduates. Students on both streams will be trained to understand how advances in the life sciences and chemistry can most effectively be translated into real outcomes of benefit to all. Close linkage to the research activities of The Advanced Centre for Biochemical Engineering (ACBE) ensures that training is built around the latest scientific discoveries and bioprocessing technologies. New micro biochemical engineering and modelling approaches to scale-down experimentation, now being taken up by our industrial collaborators, provide the basis on which students can explore a range of emerging bioprocess challenges and establish scale-up predictions to be verified in our unique pilot plant facilities. The content of the MSc programmes will benefit considerably from linkage to the department's post experience MBI Training Programme, in which some 80 industrial experts help deliver to industrial delegates, alongside MSc students. The new programme will be divided into four distinct but related elements. 1) CONVERSION ELEMENTS (45 Credits) - Biochemical Engineering Fundamentals (for science graduates). To provide the fundamentals of process engineering relevant to the handling of biological materials and the application of numerical techniques to describe biological systems. - Advanced Life Sciences (for engineering graduates). To provide insights into the function of cells and proteins and their molecular engineering or evolution to enhance efficency and bioprocess performance. 2) ADVANCED BIOCHEMICAL ENGINEERING & BIOPROCESS IMPLEMENTATION (60 Credits) These core elements will teach the design of bio-based manufacturing, i.e. fermentation & biotransformation, subsequent recovery, purification and formulation of products. This will be supported by a series of experiments on individual unit operations. New micro biochemical approaches to scale-down will broaden the student's practical knowledge. Information obtained will lead into research/design projects and be verified experimentally during week-long whole bioprocess studies in the department's pilot plant facility. 3) RESEARCH OR DESIGN PROJECT (45 Credits) The elements above are completed concurrently in the first 8 months so that the skills gained may be applied to either a design or research project. - Bioprocess Design Project For graduate scientists wishing to obtain Chartered Engineer status this is a vital part of the programme. It involves the complete design of a bioprocess, together with economic and safety analyses, and validation considerations. In 2009 the project examined the requirements for a pandemic flu vaccine. - Bioprocess Research Project Each candidate carries out an original research project of their choice, under the supervision of a member of academic staff. The students are fully integrated into one of the multidisciplinary research teams within the ACBE. Topics range from chemo-enzymatic synthesis to therapeutic antibody and stem cell bioprocessing. 4) MANAGEMENT OF BIOPROCESS VENTURES (30 Credits) This element recognises that discovery of new products and processes is often driven by small, high-tech companies. It is centred on production and presentation of a bioprocess business plan.

伦敦大学学院生物化学工程硕士课程的目标是更好地使英国公司能够获得与知识密集型、高科技（生物）制造相关的附加值。我们专门解决了最近BIGT， ABPI和IB-IGT报告中确定的实际生物工艺技能需求，并强调了工业生物技术和具有成本效益的全球医疗保健提供中的新机遇和生物工艺挑战。现有课程在提供高质量的跨学科研究生教育方面有着良好的记录。新的理学硕士课程将在此基础上开设两个课程，一个面向生物科学或化学专业毕业生，另一个面向工程专业毕业生。这两个专业的学生都将接受培训，了解生命科学和化学的进步如何最有效地转化为造福所有人的实际成果。与生物化学工程高级中心（ACBE）的研究活动密切联系，确保培训围绕最新的科学发现和生物处理技术建立。我们的工业合作伙伴正在采用新的微生化工程和建模方法进行缩小实验，为学生提供了探索一系列新兴生物工艺挑战的基础，并建立了扩大规模的预测，以在我们独特的试点工厂设施中进行验证。理学硕士课程的内容将大大受益于与该部门的岗位经验MBI培训计划的联系，在该计划中，约80名工业专家与理学硕士学生一起为工业代表提供帮助。新方案将分为四个不同但相关的部分。1)转换元素（45学分）-生化工程基础（理科毕业生）。提供与处理生物材料和应用数值技术描述生物系统相关的工艺工程基础。-高级生命科学（工科毕业生）。提供对细胞和蛋白质的功能及其分子工程或进化的见解，以提高效率和生物过程性能。高级生化工程与生物工艺实施（60学分）这些核心要素将教授生物基制造的设计，即发酵和生物转化，随后的回收，纯化和产品配方。这将得到一系列关于单个单元操作的实验的支持。新的微生化方法按比例缩小将拓宽学生的实践知识。获得的信息将用于研究/设计项目，并在该部门的试验工厂设施进行为期一周的整个生物过程研究实验验证。3)研究或设计项目（45学分）上述要素在前8个月内同时完成，以便获得的技能可以应用于设计或研究项目。生物工艺设计项目对于希望获得特许工程师身份的研究生科学家来说，这是该计划的重要组成部分。它涉及生物工艺的完整设计，包括经济和安全分析以及验证考虑。2009年，该项目审查了大流行性流感疫苗的需求。-生物工艺研究项目每位候选人在一名学术人员的监督下进行自己选择的原创性研究项目。学生们完全融入ACBE内的一个多学科研究团队。主题范围从化学酶合成到治疗性抗体和干细胞生物处理。4)生物工艺企业的管理（30学分）这一要素认识到，新产品和新工艺的发现往往是由小型高科技公司推动的。它以生物工艺商业计划的制作和呈现为中心。