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In vivo skills Masters Programme

In vivo skills Masters Programme
体内技能硕士课程
批准号:
BB/H020888/1
负责人:
Thelma Lovick
金额:
$17.28万
依托单位:
依托单位国家:
英国
项目类别:
Training Grant
财政年份:
2010
资助国家:
英国
项目状态:
已结题
起止时间:
2010 至 --

项目摘要

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中文摘要
翻译
内政部个人执照说明-道德和法律问题,动物处理,一些手术技能。模块1通用研究培训(10学分)--通过讲座课程为MDS研究生院所有学生提供的广泛培训方案,包括专业技能、道德、知识产权、统计、沟通和人际交往技能。模块2活体研究通用培训(10学分)-研讨会发展了对体内反应的综合性质的理解,数据获取所需的不同概念方法,围绕实验人工制品和翻译研究的问题,强调只有通过研究完整的动物才能揭示在分子和细胞水平上研究的机制的生物相关价值。可用于活体实验、统计设计和数据处理、考虑系统生物学和3R的技术。模块3活体精神的基本实践培训(20学分)-实时记录同步数据流,培养关键的观察意识,提高手动灵活性,识别干扰/人工制品的来源,故障排除。学生们测量几个生理参数,以及干扰他们的刺激的影响,首先是对他们自己,然后是对孤立器官的影响。集合数据的分组分析提供了使用真实数据进行统计分析的经验。行业赞助的内容包括关于侵入性记录和生物遥测的短期课程,以及客座讲座和实验室安置。单元4分子和细胞方法实践培训(20学分)--关于具体方法的介绍性讲座,然后在实验室实际应用,包括作为研究工具的分子生物学和蛋白质组学技术,以及转基因啮齿动物的使用。旨在使学生能够展示对研究分子医学和细胞生物学问题的科学基础的理解和可用研究工具的适当使用。单元5“试用者”项目(30学分)--学生通过六次为期一周的实验室实习来体验“现场”研究。他们跟踪活体研究,接受所选技术的实践能力的培训和评估,观察活体精神,等等。学生提交1份深入的报告和5份不太详细的报告(研究的基本原理、实验目的、采用的技术、获得的数据、遇到的问题及其解决方案)。模块6-研究项目(90学分)-体内实验室的全职深入研究项目,通过论文和口头或海报演示对大量研究进行评估。在以下领域提供项目:神经科学、心脏呼吸科学、组织再生和修复、干细胞和祖细胞在健康和疾病中的作用。整体学习成果-活体技术、伦理学、统计学等的实践和理论知识,通过论文、实践报告、项目报告、文献综述和演示文稿来衡量,根据总体课程目标进行加权。健康和安全-学生经过职业健康检查,必须接种当前的乙肝疫苗。如果对动物组织产生敏感性,它们可能会在最终项目中转向分子和细胞医学途径。外展活动、牧民关怀等--学生被分配了一名学术导师和研究生伙伴,以促进融入更广泛的PG机构,是大华大学和大学研究生院的成员,由博士后培训和职业发展计划(PTCDP)提供职业发展课程,媒体传播方面的培训课程(如UAR)等。职业发展指导--学术界的职业道路(PTCDP);产业选择(主要制药公司的讲座);大学研究的商业化;科学
英文摘要
Instruction for a Home Office Personal Licence - ethical and legal issues, animal handling, some surgical skills. Module 1 Generic research training (10 credits) - a broad training programme via a lectures course for all students within the College of MDS Graduate School, includes professional skills, ethics, intellectual property, statistics, communication and interpersonal skills. Module 2 Generic training for in vivo research (10 credits) - seminars develop an understanding of the integrative nature of in vivo responses, different conceptual approach required in data acquisition, issues around experimental artefact and translational research, emphasising that the biologically-relevant value of mechanisms studied at the molecular and cellular levels can only be revealed by studying the intact animal. The technology available for in vivo experimentation, statistical design and data handling, consideration of Systems Biology and the 3Rs. Module 3 Basic practical training in in vivo ethos (20 credits) - real-time recording of simultaneous data streams, developing a critical sense of observation, improving manual dexterity, recognising sources of interference/artefact, trouble shooting. Students take measurements of several physiological parameters and the effects of stimuli that perturb them, first on themselves, then progress to isolated organs. Group analysis of pooled data provides experience of statistical analysis with real data. Industry sponsored elements include short courses on invasive recording and biotelemetry, plus guest lectures and laboratory placements. Module 4 Practical training in molecular and cellular methods (20 credits) - introductory lectures on specific methodologies followed by practical application in the laboratory covering molecular biology and proteomic techniques as a research tool, and use of genetically modified rodents. Designed to enable students to demonstrate an understanding of the scientific basis and appropriate use of the research tools available to study problems in molecular medicine and cell biology. Module 5 'Taster' projects (30 credits) - students experience 'live' research with six 1-week placements in laboratories. They follow the in vivo research, receive training and assessment of practical competence in selected techniques, observe the in vivo ethos in action, etc. Students submit 1 in depth plus 5 short, less detailed reports (rationale for the research, aim of the experiments, techniques employed, data obtained, problems encountered and their resolution). Module 6 - Research project (90 credits) - in depth full time research project in an in vivo laboratory leading to a substantial piece of research assessed by thesis and oral or poster presentation. Projects offered in the following areas: Neuroscience, Cardio-respiratory sciences, Tissue regeneration and repair, Stem and progenitor cells in health and disease. Overall Learning Outcomes - practical and theoretical knowledge of in vivo techniques, ethics, statistics etc. measured by essays, practical write-ups, project reports, literature reviews and presentations, weighted according to overall course objectives. Health and Safety - students are screened by Occupational Health, and must have current Hepatitis B vaccination. If sensitisation to animal tissue develops, they may divert into the Molecular and Cellular Medicine pathway for the final project. Outreach activities, pastoral care etc. - student allocated an academic Mentor and postgraduate 'buddy' to facilitate integration into the wider PG body, is a member of the UoB and College Graduate Schools, is offered career development courses by the Postdoctoral Training and Career Development Programme (PTCDP), training courses in media communication (e.g. UAR) etc. Guidance on Career progression - career paths in academia (PTCDP); industrial options (lectures from major Pharmaceutical companies); commercialisation of university research; scientifi
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  • 批准号:
    MR/M026574/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $6.17万
  • 财政年份:
    2015
  • 负责人:
    Thelma Lovick
  • 依托单位:
Midbrain dopamine systems and control of bladder function
  • 批准号:
    G1002251/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $53.08万
  • 财政年份:
    2014
  • 负责人:
    Thelma Lovick
  • 依托单位:
Neuroactive steroids and GABAA receptor plasticity during the oestrous cycle
  • 批准号:
    G0700379/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $52.85万
  • 财政年份:
    2007
  • 负责人:
    Thelma Lovick
  • 依托单位:
海外基金