Regulation of membrane trafficking by phoshorylation during cell division.

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Each one of the several billions cells composing our body must divide to multiply during growth, healing or normal regeneration. Cell division is a complex event during which many of the processes happening inside each cell must be tightly controlled. For successful cell division to happen, some cellular events must be activated and others inhibited. Failure of certain key steps can lead to growth defects and anomalies and to various diseases such as cancer. The research I intend to perform aims at understanding how cells control the exchanges of their membrane between their envelope and interior. It is a very important aspect of cell division as it can, if perturbed, compromise proper cell renewal. Acquiring a global understanding of these events is desirable in order to progress in our knowledge of how cells function and to have the material to design new therapies for treating some related human diseases.