T-CELL MEDIATED IMMUNITY TO RICKETTSIA TSUTSUGAMUSHI

T 细胞介导的恙虫立克次体免疫

• 批准号: 3142146
• 负责人: THOMAS R JERRELLS
• 金额: $ 12.91万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-03-01 至 1993-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3142146
• 关键词: Rickettsia; T lymphocyte; antibody formation; athymic mouse; autoradiography; bacterial antigens; bacterial vaccines; cell cell interaction; cellular immunity; cytotoxic T lymphocyte; cytotoxicity; enzyme linked immunosorbent assay; flow cytometry; gel electrophoresis; host organism interaction; hybridomas; laboratory rat; lymphokines; molecular cloning; natural killer cells; nucleic acid hybridization; nucleic acid probes; tissue /cell culture; typhus

项目成果

Demonstration and partial characterization of antigens of Rickettsia rhipicephali that induce cross-reactive cellular and humoral immune responses to Rickettsia rickettsii.

诱导针对立克次体的交叉反应性细胞和体液免疫应答的扇头立克次体抗原的演示和部分表征。

• DOI: 10.1128/iai.60.12.5099-5106.1992
• 发表时间: 1992
• 期刊: Infection and immunity
• 影响因子: 3.1
• 作者: Gage,KL;Jerrells,TR
• 通讯作者: Jerrells,TR