课题基金 / 基金详情

MECHANISM OF ACTION OF GROWTH HORMONE

MECHANISM OF ACTION OF GROWTH HORMONE
生长激素的作用机制
批准号：
3151208
负责人：
H M GOODMAN
金额：
$21.45万
依托单位：
UNIV OF MASSACHUSETTS MED SCH WORCESTER
依托单位国家：
美国
项目类别：
财政年份：
1976
资助国家：
美国
项目状态：
已结题
起止时间：
1976-05-01 至 1986-04-30
来源：
https://reporter.nih.gov/project-details/3151208
关键词：
adipose tissue animal age group cell free system cell membrane estradiol glucose metabolism homeostasis hormone regulation /control mechanism insulinlike factor mitochondria monoclonal antibody protease inhibitor pyruvate dehydrogenase somatotropin triiodothyronine

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中文摘要
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英文摘要
Using epididymal fat tissue and isolated cells, the studies are directed at uncovering the relationships of the various effects of growth to each other and to hormone binding. The events involved in the initial insulin-like response and the cellular processes that counter these effects will be explored in detail in an effort to determine whether the spectrum of growth hormone effects arise from a single unique interaction between the tissue and the hormone or from a series of independent actions. Ultimately, it is intended to relate these early rapid events to the overall process of growth promotion and regulation.
期刊论文(18)
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会议论文
Turnover of growth hormone receptors in rat adipocytes.
大鼠脂肪细胞中生长激素受体的周转。
DOI： 10.1210/endo-116-5-1796
发表时间： 1985
期刊： Endocrinology
影响因子： 4.8
作者： [Gorin,E, Goodman,HM]
通讯作者： Goodman,HM
Pituitary secretions related to adrenocorticotropic hormone induce sensitivity of adipose tissue to the insulin-like actions of growth hormone.
与促肾上腺皮质激素相关的垂体分泌物诱导脂肪组织对生长激素的胰岛素样作用的敏感性。
DOI： 10.1159/000124719
发表时间： 1987
期刊： Neuroendocrinology
影响因子： 4.1
作者： [Coiro,V, Goodman,HM]
通讯作者： Goodman,HM
Covalent binding of growth hormone to surface receptors on rat adipocytes.
生长激素与大鼠脂肪细胞表面受体的共价结合。
DOI： 10.1210/endo-114-4-1279
发表时间： 1984
期刊： Endocrinology
影响因子： 4.8
作者： [Gorin,E, Goodman,HM]
通讯作者： Goodman,HM
Binding and degradation of [125I]human growth hormone in rat adipocytes.
[125I]人生长激素在大鼠脂肪细胞中的结合和降解。
DOI： 10.1210/endo-115-2-467
发表时间： 1984
期刊： Endocrinology
影响因子： 4.8
作者： [Gorin,E, Grichting,G, Goodman,HM]
通讯作者： Goodman,HM
共 18 条
    INTERDISCIPLINARY STUDIES OF HORMONE FUNCTION
    INTERDISCIPLINARY STUDIES OF HORMONE FUNCTION
    INTERDISCIPLINARY STUDIES OF HORMONE FUNCTION
    INTERDISCIPLINARY STUDIES OF HORMONE FUNCTION