课题基金 / 基金详情

ANALYSIS OF MONONUCLEAR PHAGOCYTE DIFFERENTIATION

ANALYSIS OF MONONUCLEAR PHAGOCYTE DIFFERENTIATION
单核吞噬细胞分化分析
批准号：
3165719
负责人：
THOMAS B TOMASI
金额：
$11.9万
依托单位：
ROSWELL PARK CANCER INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
1987
资助国家：
美国
项目状态：
已结题
起止时间：
1987-09-01 至 1989-08-31
来源：
https://reporter.nih.gov/project-details/3165719
关键词：
cell differentiation cell population study flow cytometry human tissue immunoregulation immunosuppression macrophage membrane activity monoclonal antibody neoplasm /cancer immunology surface antigens tissue /cell culture

项目摘要

项目成果

THOMAS B TOMASI的其他基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This research project essentially involves an analysis of macrophage differentiation through a study of a series of murine tumor cell lines, which show various degrees of maturation arrest. Many alloantigens and hybridoma-defined cell surface components are becoming available for further definition of subpopulations of cells of macrophage lineages, and these components will be used in a general study of differentiation arrest, intratumor heterogeneity, and potential for further induction of differentiation in these cell lines. Particular emphasis is being placed on functional properties (antigen presentation, tumoricidal activity, phagocytosis) and their correlation with cell surface phenotypic markers as defined by monoclonal antibodies at specific differentiation stages. (MB)
期刊论文(17)
专著(0)
科研奖励(0)
会议论文
Lym 7.2: monoclonal antibody defining an alloantigen similar or identical to Ly 7.2.
Lym 7.2：定义与Ly 7.2相似或相同的同种异体抗原的单克隆抗体。
DOI： 10.1089/hyb.1.1982.1.227
发表时间： 1982
期刊： Hybridoma
影响因子： --
作者： [Lanier,LL, Warner,NL]
通讯作者： Warner,NL
Transplantation resistance to a murine plasmacytoma lacking MHC determinants.
对缺乏 MHC 决定簇的小鼠浆细胞瘤的移植抗性。
DOI： 10.1016/0008-8749(90)90114-7
发表时间： 1990
期刊： Cellular immunology
影响因子： 4.3
作者： [Daley,MJ, Williams,TJ, Giorgi,J, Warner,NL]
通讯作者： Warner,NL
Expression of Lyt-1 antigen on certain murine B cell lymphomas.
DOI： 10.1084/jem.153.4.998
发表时间： 1981-04-01
期刊： The Journal of experimental medicine
影响因子： --
作者： [Lanier LL, Warner NL, Ledbetter JA, Herzenberg LA]
通讯作者： Herzenberg LA
Characterization and functional properties of tumor cell lines in accessory cell replacement assays.
辅助细胞替代测定中肿瘤细胞系的表征和功能特性。
DOI： --
发表时间： 1982
期刊： Journal of immunology (Baltimore, Md. : 1950)
影响因子： --
作者： [Walker,EB, Lanier,LL, Warner,NL]
通讯作者： Warner,NL
共 12 条
    Epigenetic Regulation of Immune Genes in Cancer Treatment and Vaccine Protocols
    Epigenetic Regulation of Immune Genes in Cancer Treatment and Vaccine Protocols
    Epigenetic Regulation of Immune Genes in Cancer Treatment and Vaccine Protocols
    Epigenetic Regulation of Immune Genes in Cancer Treatment and Vaccine Protocols