AUTOLOGUS MARROW TRANSPLANTATION
AUTOLOGUS MARROW TRANSPLANTATION
批准号:
3167465
负责人:
CLARENCE DEAN BUCKNER
金额:
$16.62万
依托单位国家:
美国
项目类别:
财政年份:
1980
资助国家:
美国
项目状态:
已结题
起止时间:
1980-04-01 至 1986-05-31
关键词:
autologous transplantation bone marrow preservation bone marrow transplantation combination cancer therapy homologous transplantation human subject human therapy evaluation leukocyte antigen typing lymphoma monoclonal antibody neoplasm /cancer chemotherapy neoplasm /cancer immunotherapy neoplasm /cancer remission /regression neoplasm /cancer therapy
中文摘要
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英文摘要
The specific aims of this proposal are to evaluate the effectiveness of
autologous marrow transplantation (AMT) in patients with acute leukemia and
malignant lymphoma. Pretranplant treatment regimens previously tested or
being tested in our syngeneic and allogeneic programs will be used with AMT
in order to allow comparisons of the relapse rate using the different tupes
of marrow. The long-term goal is to ascertain whether or not autologous
marrow can be used successfully as an alternative to syngeneic or
allogeneic marrow in patients who do not have suitable donors. We will
evaluate the effects of posttransplant chemotherapy and the incubation of
marrow with monoclonal antibodies in preventing posttransplant relapses.
期刊论文(18)
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DOI:
10.1097/00007890-198807000-00010
发表时间:
1988
期刊:
Transplantation
影响因子:
6.2
作者:
[Wingard,JR, Sostrin,MB, Vriesendorp,HM, Mellits,ED, Santos,GW, Fuller,DJ, Braine,HG, Yeager,AM, Burns,WH, Saral,R]
通讯作者:
Saral,R
Elimination of Daudi lymphoblasts from human bone marrow using avidin-biotin immunoadsorption.
使用抗生物素蛋白-生物素免疫吸附消除人骨髓中的道迪淋巴母细胞。
DOI:
--
发表时间:
1986
期刊:
Blood
影响因子:
20.3
作者:
[Berenson,RJ, Bensinger,WI, Kalamasz,D, Martin,P]
通讯作者:
Martin,P
DOI:
10.1016/s0308-2261(86)80003-0
发表时间:
1986
期刊:
Clinics in haematology
影响因子:
--
作者:
[Appelbaum,FR, Buckner,CD]
通讯作者:
Buckner,CD
Allogeneic bone marrow transplantation in irradiated adult rabbits.
受辐射成年兔的同种异体骨髓移植。
DOI:
10.1097/00007890-198709000-00005
发表时间:
1987
期刊:
Transplantation
影响因子:
6.2
作者:
[Bigelow,CL, Adler,LT, Appelbaum,FR]
通讯作者:
Appelbaum,FR
DOI:
--
发表时间:
1987
期刊:
Cancer treatment reports
影响因子:
--
作者:
[Appelbaum,FR]
通讯作者:
Appelbaum,FR
共 16 条
INTERNATIONAL SOCIETY FOR EXPERIMENTAL HEMATOLOGY
-
批准号:3435680
-
项目类别:
-
资助金额:$2.05万
-
财政年份:1990
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位:
AUTOLOGOUS MARROW TRANSPLANTATION
-
批准号:3094251
-
项目类别:
-
资助金额:$141.38万
-
财政年份:1989
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位:
AUTOLOGOUS MARROW TRANSPLANTATION
-
批准号:3094254
-
项目类别:
-
资助金额:$148.47万
-
财政年份:1989
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位:
AUTOLOGOUS MORROW TRANSPLANTATION
-
批准号:2092716
-
项目类别:
-
资助金额:$81.51万
-
财政年份:1989
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位:
AUTOLOGOUS MORROW TRANSPLANTATION
-
批准号:3094256
-
项目类别:
-
资助金额:$79.91万
-
财政年份:1989
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位:
AUTOLOGOUS MARROW TRANSPLANTATION
-
批准号:3094252
-
项目类别:
-
资助金额:$75.0万
-
财政年份:1989
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位:
AUTOLOGOUS MORROW TRANSPLANTATION
-
批准号:2092717
-
项目类别:
-
资助金额:$87.18万
-
财政年份:1989
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位:
AUTOLOGOUS MARROW TRANSPLANTATION
-
批准号:3094255
-
项目类别:
-
资助金额:$158.58万
-
财政年份:1989
-
负责人:CLARENCE DEAN BUCKNER
-
依托单位: