OBJECTIVE GRADING OF PROSTATE CARCINOMA

细胞学和组织学样本中细胞核的DNA倍体模式 将用于提供肿瘤诊断和预后信息。 我们 快速，计算机控制，基于视频的显微光度计系统允许 在几分钟内记录DNA倍体模式，具有统计学有效性 样本量，从而使这种有价值的方法作为常规实用 临床实验室测试。 其目的是使方法标准化 为此目的，收集和检查临床数据库， 倍性模式与临床意义，以建立客观的措施 用于倍性模式评估，并建立对 非整倍性的检测。 一种廉价的微处理器显微镜 附件和图形显示已被设计为一个原型， 实用病理学实验仪器。 （三）

DNA ploidy patterns in cell nuclei from cytologic and histologic samples will be used to provide tumor diagnostic and prognostic information. Our rapid, computer-controlled, video-based microphotometer system allows the recording of DNA-ploidy patterns within minutes, with statistically valid sample sizes, thus making this valuable method practical as a routine clinical laboratory test. It is intended to standardize the methodology for this purpose, to assemble and examine a clinical database to correlate ploidy patterns with clinical implications, to establish objective measures for ploidy pattern evaluation, and to establish the sensitivity for the detection of aneuploidy. An inexpensive, microprocessor-based microscope attachment and graphic display has been designed as a prototype for a practical pathology laboratory instrument. (3)