Development and commercial exploitation of a novel fungicide designed to combat resistance in agriculture
Development and commercial exploitation of a novel fungicide designed to combat resistance in agriculture
批准号:
BB/M022161/1
负责人:
Simon Avery
金额:
$14.47万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2015
资助国家:
英国
项目状态:
已结题
起止时间:
2015 至 --
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Fungi can be devastating as pathogens of food-crops, of humans and as food spoilage organisms. There is great potential value in new, effective treatments for controlling fungal growth. Through previous BBSRC-funded work, we discovered a novel combination of two agents with greatly amplified inhibitory action against fungi. Combination treatments are highly sought as they counter drug resistance and use smaller amounts of active agents. Our subsequent Pathfinder project has identified a very promising commercial path for exploiting this technology: as a fungicide to help preserve food crops. The agricultural fungicide market was forecast to be worth $12,125 million in 2014, and is growing. Through the Pathfinder, four important agri-chemical companies have formally expressed their interest in our findings and in potential development of a new fungicide. This Follow on Fund proposal combines key technical work with commercial development in order to take the technology towards market.
期刊论文(8)
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DOI:
10.1038/srep16700
发表时间:
2015-11-17
期刊:
Scientific reports
影响因子:
4.6
作者:
[Moreno-Martinez E, Vallieres C, Holland SL, Avery SV]
通讯作者:
Avery SV
Synergistic combinations targeting translation fidelity and diverse fungal pathogens
针对翻译保真度和多种真菌病原体的协同组合
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Vallieres, C]
通讯作者:
Vallieres, C
A novel fungicide target for crop protection from fungal pathogens
一种保护作物免受真菌病原体侵害的新型杀菌剂靶点
DOI:
--
发表时间:
2019
期刊:
影响因子:
--
作者:
[Young T]
通讯作者:
Young T
DOI:
10.1016/bs.ampbs.2017.01.001
发表时间:
2017
期刊:
Advances in microbial physiology
影响因子:
--
作者:
[C. Vallieres;S. Avery]
通讯作者:
C. Vallieres;S. Avery
The Candidate Antimalarial Drug MMV665909 Causes Oxygen-Dependent mRNA Mistranslation and Synergizes with Quinoline-Derived Antimalarials.
候选抗疟药MMV665909导致氧依赖性mRNA误译,并与喹啉衍生的抗疟药协同作用。
DOI:
10.1128/aac.00459-17
发表时间:
2017-09
期刊:
Antimicrobial agents and chemotherapy
影响因子:
4.9
作者:
[Vallières C, Avery SV]
通讯作者:
Avery SV
共 7 条
Development and exploitation of a bioactives-free technology for tackling fungal threats to food security, goods and health
-
批准号:BB/V003623/1
-
项目类别:Research Grant
-
资助金额:$61.51万
-
财政年份:2021
-
负责人:Simon Avery
-
依托单位:
Spoilage-yeast metabolism, reduced-sugar formulations and implications for food preservation
-
批准号:BB/T014784/1
-
项目类别:Research Grant
-
资助金额:$55.9万
-
财政年份:2021
-
负责人:Simon Avery
-
依托单位:
Exploitation of a novel fungicide for preventing fungal contamination and deterioration of products and materials
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批准号:BB/P02369X/1
-
项目类别:Research Grant
-
资助金额:$25.56万
-
财政年份:2017
-
负责人:Simon Avery
-
依托单位:
Development of a UK-Brazil partnership to tackle fungal food spoilage and improve food security
-
批准号:BB/P017207/1
-
项目类别:Research Grant
-
资助金额:$4.28万
-
财政年份:2017
-
负责人:Simon Avery
-
依托单位:
Tackling resistance to food preservatives: Heterogeneity in fungal spore populations
-
批准号:BB/N017129/1
-
项目类别:Research Grant
-
资助金额:$47.55万
-
财政年份:2016
-
负责人:Simon Avery
-
依托单位:
Adaptation to environmental stress by evolution of non-genotypic heterogeneity within microbial populations
-
批准号:NE/L006553/1
-
项目类别:Research Grant
-
资助金额:$45.87万
-
财政年份:2014
-
负责人:Simon Avery
-
依托单位:
Market assessment and evaluation of an appropriate commercial path for a novel fungicide
-
批准号:BB/M011852/1
-
项目类别:Research Grant
-
资助金额:$0.98万
-
财政年份:2014
-
负责人:Simon Avery
-
依托单位:
Stress resistance and the essential iron-sulphur cluster protein Rli1
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批准号:BB/I000852/1
-
项目类别:Research Grant
-
资助金额:$42.82万
-
财政年份:2011
-
负责人:Simon Avery
-
依托单位:
The importance of non-genotypic diversity for the fitness of microbial populations
-
批准号:NE/E005969/1
-
项目类别:Research Grant
-
资助金额:$42.67万
-
财政年份:2007
-
负责人:Simon Avery
-
依托单位:
国内基金
海外基金
低辐射空间环境下商用多核处理器层次化软件容错技术研究
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批准号:90818016
-
项目类别:重大研究计划
-
资助金额:50.0万元
-
批准年份:2008
-
负责人:傅忠传
-
依托单位: