BIOLOGICAL CONSTRAINTS ON TUNING IN THE INNER EAR
内耳调谐的生物学限制
基本信息
- 批准号:3216160
- 负责人:
- 金额:$ 18.55万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1983
- 资助国家:美国
- 起止时间:1983-07-01 至 1995-06-30
- 项目状态:已结题
- 来源:
- 关键词:Anura acoustic nerve auditory discrimination auditory feedback auditory pathways auditory stimulus auditory threshold shift biological information processing cell membrane ear hair cell efferent nerve evoked potentials fresh water environment innervation neuroanatomy noise psychoacoustics sequential perception single cell analysis sound frequency stimulus /response temperature vibration voltage /patch clamp
项目摘要
DESCRIPTION: (Adapted from the Applicant's Abstract.) The overall goal of
the proposed research is a deeper understanding of the anatomical and
neural bases of frequency selectivity in the vertebrate auditory system.
In particular, the primary objectives of the proposed research are two: to
provide insights into the mechanisms underlying stimulus interactions which
affect tuning in the vertebrate auditory system, and to gain an
understanding and appreciation of the cellular bases of frequency
resolution. To accomplish the first of these objectives the investigators
will (1) elucidate the underlying relationship between two-tone suppression
and tuning in the auditory nerve by examining and comparing their
temperature dependencies, (2) quantify the effect of contralateral sound on
the tuning properties of single auditory nerve fibers, and (3)
systematically study the effect of low-level vibratory stimulation on the
auditory tuning properties of individual low-frequency auditory neurons.
To carry out the second objective, the applicants will (1) precisely
characterize membrane currents of auditory hair cells to determine their
temperature dependencies, and thus to assess their contribution to tuning,
and (2) relate anatomical fine structure (cell body dimensions, axon
dimensions, innervation pattern) to tuning properties of identified
auditory nerve fibers. Such data that result from this structure-function
approach will be rich in implications regarding the anatomical and neural
substrate underlying the processing of complex sounds, and that this work
will serve as a model for understanding fundamental problems of human
speech and music perception in adverse (noisy) environments.
描述:(改编自申请人摘要)的总体目标
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
PETER M. NARINS其他文献
PETER M. NARINS的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('PETER M. NARINS', 18)}}的其他基金
AUDITORY SYSTEM RESPONSE TO AIRBORNE AND SEISMIC STIMULI
听觉系统对空气和地震刺激的反应
- 批准号:
6605664 - 财政年份:1983
- 资助金额:
$ 18.55万 - 项目类别:
LIMITS OF TEMPORAL ENCODING IN THE AUDITORY SYSTEM
听觉系统中时间编码的局限性
- 批准号:
3216164 - 财政年份:1983
- 资助金额:
$ 18.55万 - 项目类别:
TEMPORAL PROCESSING OF AUDITORY SIGNALS IN NOISE
噪声中听觉信号的时间处理
- 批准号:
3399822 - 财政年份:1983
- 资助金额:
$ 18.55万 - 项目类别:
AUDITORY SYSTEM RESPONSE TO AIRBORNE AND SEISMIC STIMULI
听觉系统对空气和地震刺激的反应
- 批准号:
6766891 - 财政年份:1983
- 资助金额:
$ 18.55万 - 项目类别:
From infra- to ultrasound: Diversity in acoustic processing by the vertebrate ear
从红外线到超声波:脊椎动物耳朵声学处理的多样性
- 批准号:
7683362 - 财政年份:1983
- 资助金额:
$ 18.55万 - 项目类别:
From infra- to ultrasound: Diversity in acoustic processing by the vertebrate ear
从红外线到超声波:脊椎动物耳朵声学处理的多样性
- 批准号:
7148607 - 财政年份:1983
- 资助金额:
$ 18.55万 - 项目类别:
From infra- to ultrasound: Diversity in acoustic processing by the vertebrate ear
从红外线到超声波:脊椎动物耳朵声学处理的多样性
- 批准号:
7626689 - 财政年份:1983
- 资助金额:
$ 18.55万 - 项目类别: