TREATMENT OF DRUG ABUSERS WITH BORDERLINE PERSONALITY

边缘人格吸毒者的治疗

• 批准号: 3215068
• 负责人: Marsha Linehan
• 金额: $ 20.09万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-09-30 至 1996-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3215068
• 关键词: cognitive behavior therapy; community health services; drug abuse therapy; emotions; female; functional ability; handbook; health care service utilization; human subject; human therapy evaluation; interpersonal relations; interview; neuropsychological tests; personality disorders; quality of life; substance abuse related disorder; suicide; urinalysis; videotape /videodisc

The general aim of this research proposal is to develop an effective treatment intervention for individuals who meet criteria for both drug use disorders and for borderline personality disorder (BPD). Specific aims are to pilot test and modify as needed an existing cognitive behavioral treatment (Dialectical Behavior Therapy; DBT) which has been shown to be effective for severely dysfunctional, chronically suicidal women who meet criteria for BPD. We will also develop and pilot an assessment battery for evaluating treatment with this population. To accomplish these objectives, we plan to conduct a one year pilot treatment outcome study with approximately 20 subjects meeting criteria for both drug use disorder and for BPD. Subjects will be randomly assigned to a DBT pilot treatment condition (n=10) or to a community treatment-as-usual (TAU) condition (n=10). Outcomes targeted and measured will include reductions in frequency and severity of substance abuse, suicidal behaviors, therapy-interfering behaviors, dysfunctional behaviors (other than substance abuse and suicidal behaviors) that severely limit the quality of life and negative affect and enhancement of general functioning and interpersonal skills. DBT therapists will be the PI as well as experienced psychotherapists and drug abuse counselors trained in DBT by the PI. The major outcome assessment battery will be administered at pre-, 4-month, 8-month, and 12-month points (immediately following the end of treatment) treatment points. Additional daily patient ratings, weekly client and therapist ratings by DBT subjects and random drug testing for all subjects will be conducted. Observation of treatment sessions (through one-way mirrors and by video), weekly case consultation meetings, and ongoing assessments will be used to monitor and document treatment delivery and make necessary changes to the treatment and assessment protocols.

这项研究的总体目标是制定一项有效的 对同时符合两种药物标准的个体进行治疗干预 使用障碍和边缘型人格障碍（BPD）。 具体 目的是试点测试和修改需要现有的认知 行为治疗（辩证行为疗法; DBT）， 对严重功能障碍，慢性自杀 符合BPD标准的女性。 我们还将开发和试点 用于评价该人群治疗的评估组合。 到 为了实现这些目标，我们计划进行为期一年的试点， 约20例符合标准的受试者的治疗结局研究 药物使用障碍和BPD 受试者将被随机 分配到DBT试点治疗条件（n=10）或社区 常规治疗（TAU）条件（n=10）。 目标成果和 所衡量的将包括减少物质的频率和严重程度 虐待、自杀行为、治疗干扰行为、功能障碍 行为（药物滥用和自杀行为除外）， 严重限制生活质量和负面影响及提高 一般功能和人际交往能力。 DBT治疗师将 PI以及经验丰富的心理治疗师和药物滥用咨询师 接受过PI的DBT培训。 主要结局评估组合将包括 在术前、4个月、8个月和12个月时（立即）给药 治疗结束后）治疗点。 额外的每日 DBT受试者的患者评级、每周客户和治疗师评级， 将对所有受试者进行随机药物测试。 观察 治疗疗程（通过单向镜和视频），每周一次 咨询会议和正在进行的评估将用于监测 并记录治疗交付，并对 治疗和评估方案。