VOCAL-LEARNING MODEL FOR NEURONAL BASIS OF COGNITION

认知神经元基础的声音学习模型

• 批准号: 3216009
• 负责人: FERNANDO NOTTEBOHM
• 金额: $ 13.97万
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1982
• 资助国家: 美国
• 起止时间: 1982-03-01 至 1991-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3216009
• 关键词: Aves; animal communication behavior; auditory discrimination; auditory stimulus; biological clocks; brain mapping; cerebral dominance; dendrites; electrophysiology; ethology; experience; experimental brain lesion; gender difference; histochemistry /cytochemistry; learning; neuropsychology; perception; psychobiology; sex behavior; vocalization

Work to be supported by this grant will continue to investigate the anatomy and physiology of the song control system of birds. Specific aims are to better understand, 1) the relation between production and perception of learned song; 2) brain asymmetries and sexual dimorphism that may occur in the perception of learned song; 3) the rules that govern the recognition of conspecific song and the preference that females show for the song of some individual birds; 4) the anatomical and physiological regulation of song learning; 5) the relation between pathways used for song learning and pathways governing other reproductive behaviors. Information on these matters should uncover interesting principles of brain function that can then be related to learning. The P.I. expects that these insights will be applicable to other systems, including vocal learning and brain function in humans. Information derived from these various related projects might also help understand how the newly discovered phenomenon of neuronal replacement in adult avian brain relates to how song learning circuits are organized. Health relatedness: The P.I. believes that the kinds of circuit plasticity that birds seem to use for learning -- neurite growth and retraction, formation and culling of synapses, neurogenesis - - will, once understood at the molecular level form the basis of inducible and controlled brain self-repair. In addition, a better understanding of the factors that restrict or encourage learning could be of great benefit to humans. The song learning system of birds is good material to study these matters.

由这笔赠款支持的工作将继续调查 鸟类鸣叫控制系统的解剖学和生理学。 具体目的是为了更好地理解，1) 习得歌曲的产生和感知；2)大脑不对称和 在对习得歌曲的知觉中可能出现的性别二形性； 3)管理同种歌曲识别的规则和 女性对某个人的歌曲表现出的偏爱 鸟类；4)歌唱的解剖和生理调节 学习；5)歌曲学习路径之间的关系 以及控制其他生殖行为的途径。信息 在这些问题上应该揭示大脑的有趣原理 功能，然后才能与学习相关。私家侦探希望 这些见解将适用于其他系统，包括 人类的发声学习和大脑功能。派生的信息 从这些不同的相关项目中也可能有助于理解 成人新发现的神经元替代现象 鸟脑与歌曲学习回路的组织方式有关。 与健康相关：私家侦探认为 鸟类似乎用来学习的可塑性--轴突生长 以及突触的收缩、形成和剔除，神经发生- -意志，一旦在分子水平上被理解，就形成了 诱导和控制的大脑自我修复。此外，一个更好的 了解限制或鼓励学习的因素 可能对人类有很大的好处。的歌曲学习系统 鸟类是研究这些问题的好材料。