Development of a Herbicide Discovery Platform for commercialisation

这项建议的目的是开发一种利用申请人实验室开发的新的高通量系统来筛选具有选定作用模式的除草剂的技术。它建立在产生对抑制植物生长所需特定过程的化学品更敏感的敏感基因突变植物的基础上。与利用我们基因系统独特特征的已经建立的除草剂靶标发现技术相结合，拟议的技术将允许申请者开发从化学发现到目标发现的除草剂发现管道。这些技术结合在一起将通过各种途径为商业活动提供基础。我们由探路者奖资助的市场研究表明，业界对该平台有相当大的兴趣，它有可能产生可观的收入。

The aim of this proposal is to develop a technology for screening of herbicides with selected modes of action using a novel high throughput system developed in the applicants laboratory.It builds on the generation of sensitised genetic mutant plants that are more sensitive to chemicals that inhibit specific processes required for plant growth.Together with an already established technology for herbicide target discovery that exploits unique characteristics of our genetic system, the proposed technology will allow the applicant to develop of a herbicide discovery pipeline that goes from chemical discovery through to target discovery.Together these technologies will provide the basis of a commercial activity through a variety of routes.Our market research funded through a Pathfinder award indicates that there is considerable interest from industry in the platform and it has the potential to generate considerable revenues.