POLLUTANT INTERACTIONS WITH RED CELLS

杜克大学海洋生物医学中心推动和整合 水生生物的多学科研究，重点是 环境健康问题。该中心正在进行的计划说明 海洋生物的巨大多样性如何成为一种优势 在梳理分子基础的基本机制时， 细胞和组织在正常和病理状态下的行为。 杜克大学海洋生物医学中心的持续支持是 要求允许在已建立的 在医学和海洋各方面都有经验的调查人员 科学。海洋生物医学中心行政核心单位 促进有关问题的研究和信息交流 与环境健康有关的海洋科学。与……紧密联系 杜克大学医学中心促进了研究成果的转移 该中心的调查结果向医学界通报。行政单位 还协调讲座、会议、访问学者计划和 出版双月刊时事通讯《环境》。设施和服务 单位向中心的参与者和同事提供一个号码 能够分析的实验室服务和特殊设备项目 污染物浓度和影响。研究中的参与者 该中心的单位利用海洋生物进行研究，这些研究具有 澄清可能敏感的基本过程的可能性 对环境的压力。正在进行的计划包括以下方面的研究：1) 化学污染物对呼吸道蛋白质和电子的影响 运输蛋白，2)金属和非金属污染物对蛋白质的影响 各种无脊椎动物幼虫的发育，3)污染物毒理学使用 血液作为模型器官，4)河口污染的行为方面和 海洋系统，5)金属和非金属污染物对 运输过程，6)污染物对基因激活的影响和 胚胎发育；7)痕量金属解毒机制 在海洋生物中。研究单位资助可行性研究以延长 并整合这些正在进行的研究项目。

The Duke University Marine Biomedical Center promotes and integrates multidisciplinary research on aquatic organisms with a focus on environmental health problems. Ongoing programs of the Center illustrate how the great diversity among marine organisms can be used to an advantage in sorting out the fundamental mechanisms which underlie molecular, cellular and organismic behavior in normal and pathological states. Continued support for the Duke University Marine Biomedical Center is requested to allow for further productive interactions between established investigators having experience in various aspects of medical and marine sciences. The Administrative Core Unit of the Marine Biomedical Center stimulates research and information exchange concerning problems in the marine sciences that are related to environmental health. Strong ties with the Duke University Medical Center facilitate the transfer of research findings of the Center to the medical community. The Administrative Unit also coordinates lectures, meetings, a Visiting Scholar Program and publishes a bimonthly newsletter, ENVIRONS. The Facilities and Services Unit makes available to participants and associates of the Center a number of laboratory services and special equipment items capable of analyzing pollutant concentrations and effects. The participants in the Research Unit of the Center make use of marine organisms in studies which have high potential for clarification of fundamental processes which may be sensitive to environmental stress. Ongoing programs include studies concerning: 1) the effects of chemical pollutants on respiratory proteins and electron transport proteins, 2) the effects of metal and non-metal pollutants on larval development of various invertebrates, 3) pollutant toxicology using blood as a model organ, 4) behavioral aspects of pollution in estuarine and marine systems, 5) the effect of metal and non-metal pollutants on transport processes, 6) pollutant effects on gene activation and embryological development, and 7) mechanisms of trace metal detoxification in marine organisms. The Research Unit funds feasibility studies to extend and integrate these ongoing research programs.