FOOD SELECTION AND REGULATION IN EATING DISORDERS

饮食失调症的食物选择和调节

• 批准号: 3241490
• 负责人: BARBARA Jean ROLLS
• 金额: $ 16.71万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-01 至 1993-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3241490
• 关键词: anorexia nervosa; behavior test; biological information processing; bulimia nervosa; caloric dietary content; diet; diet route /schedule; eating; human subject; hunger; nutrition related tag; pleasure; preference; questionnaires; satiations; taste

The processes which initiate, maintain and terminate eating in disordered individuals have not been identified. We propose to evaluate the responses of subjects with anorexia nervosa, bulimia nervosa, or chronic dieting behavior to manipulations of energy density, food type, portion size, deprivation and food selection in naturalistic and laboratory settings before and after inpatient treatment. Four main hypotheses will be tested: First, that the eating behavior of eating behavior of eating disordered individuals differs quantitatively from that of the normal population on parameters such as rate of ingestion, dietary selection and onset of satiety. Second, that eating disordered subjects fails to adjust intake according to energy density relative to non- disordered subjects. Third, that the groups will show differential development of sensory-specific satiety and changes in rating of affective and cognitive variables to foods after test meal consumption. Finally, that the abnormal characteristics recorded in eating disordered patients will be normalized following treatment. These hypotheses will be tested in the following experiments which will systematically assess regulation, food selection and responses to foods: 1. Ability to regulate caloric intake will be investigated using a high and low-calorie preload or a liquid diet. The degree to which subjects compensate for caloric content will indicate sensitivity to internal regulatory cues. 2. Responses to familiar foods which are high or low- calorie will be studied. Food selection, amount consumed, rate of eating and ratings of sensory, affective and cognitive variables will provide evidence for disturbances of basic ingestive processes. 3. The influence of three levels of deprivation on eating behavior will be monitored. Adjustment of intake following deprivation will indicate responsiveness to internal signals of hunger. 4. Food selection and energy intake in a cafeteria and laboratory setting will be compared before and after treatment. The extent to which normalized levels of intake have been restored will be recorded. These experiments will permit us to identify parameters which characterize disordered eating. Such information will enhance not only our understanding of the pathogenesis of eating disorders but will increase our knowledge of the mechanisms underlying eating in normals.

启动、维持和终止进食的过程 尚未发现精神失常的人。 我们建议 评价神经性厌食症、贪食症 神经性或慢性节食行为对能量的操纵 密度、食物类型、分量大小、剥夺和食物选择 在住院前后的自然和实验室环境中， 治疗 将检验四个主要假设：第一， 饮食失调者的饮食行为 在数量上与正常人群不同， 参数，如摄入率，饮食选择和发病 饱足感 第二，饮食失调的受试者未能 根据能量密度调整摄入量， 无序的主题 第三，各群体将表现出差异化， 感觉特异性饱腹感的发展和 试验餐后食物的情感和认知变量 消费 最后，异常特征记录 饮食失调的患者将正常化， 治疗 这些假设将在下面进行检验 这些实验将系统地评估监管、食品 对食物的选择和反应：1。 调节热量的能力 将使用高热量和低热量预负荷来研究摄入量 或流质饮食。 受试者补偿的程度 卡路里含量将指示对内部调节的敏感性， 线索 2. 对熟悉食物的反应有高有低- 卡路里将被研究。 食物选择，消费量，价格 以及感官、情感和认知变量的评分 会提供基础摄食紊乱的证据 流程. 3. 三种剥夺水平对儿童智力的影响 饮食行为将受到监控。 以下摄入量的调整 剥夺将表明对内部信号的反应， 饥饿 4. 自助餐厅的食物选择和能量摄入， 实验室设置将在治疗前后进行比较。 摄入量恢复正常水平的程度 将被记录。 这些实验将使我们能够识别 这些参数是饮食失调的特征。 此类信息 不仅能加深我们对 饮食失调，但会增加我们的知识的机制， 在正常人的饮食中。