IWYP Call 2: Transforming yield through source-sink synchronisation

IWYP 呼吁 2：通过源-汇同步改变产量

• 批准号: BB/S01280X/1
• 负责人: Matthew Paul
• 金额: $ 123.09万
• 依托单位: Rothamsted Research
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FS01280X%2F1
• 关键词: IWYP; Call; Transforming; yield; through

The greatest improvements in crop yields are likely to come from optimising and coordinating the whole plant source-sink system to fully realise photosynthetic potential as grain yield. Emerging research on trehalose 6-phosphate (T6P) has shown that T6P plays a key role in coordinating source and sink activities in crops. Recent novel chemical biology has been used to modify T6P in such a way that it can be used to screen for yield traits. Using T6P precursors as a chemical spray to wheat during early grain filling stimulates starch synthesis in grain increasing starch content, grain size and overall yield by up to 20%. Significantly, this is accompanied by increased photosynthesis in flag leaves due to the enhanced demand created by the sink. This shows that photosynthetic potential may be masked by sink limitations. In addition to its effect on grain size T6P influences initiation and setting of grain number. Through analysis of the response of genetically diverse high-yielding germplasm, T6P precursor will be used as a smart screen for true photosynthetic potential, grain number and size potential as well as biomass and harvest index affected by the harmonisation of source and sink activity. Genome wide association mapping will be performed to discover genomic regions associated with high source and sink and quantitative trait loci will be identified. Given recent examples of association of trehalose phosphate phosphatase genes with crop yield attention will also be given to finding SNPs in trehalose pathway genes as likely genetic variants underlying traits. Outputs will be used at the IWYP Hub to design strategic crosses that maximise genetic complementarity of both source and sink for high yield delivered to breeders in developed and developing countries via the International Wheat Improvement Network.

作物产量的最大改善可能来自于优化和协调整个植物源-库系统，以充分实现光合作用潜力与粮食产量。新近对海藻糖6-磷酸(T6P)的研究表明，T6P在协调作物源库活动中起着关键作用。最近新的化学生物学已经被用来对T6P进行修饰，使其可以用于筛选产量性状。在小麦灌浆早期使用T6P前体作为化学喷雾剂，可以刺激籽粒中淀粉的合成，使淀粉含量、籽粒大小和总产量提高高达20%。值得注意的是，这伴随着旗叶光合作用的增加，这是由于汇产生的增强的需求。这表明，光合作用潜力可能被库限制所掩盖。除了对晶粒度的影响外，T6P还影响粒数的形成和形成。通过对遗传多样性的高产种质的响应分析，T6P前体将被用作真实光合势、籽粒数和大小潜力以及生物量和收获指数受源和库活动协调影响的智能屏幕。将进行全基因组关联作图，以发现与高源库相关的基因组区域，并将确定数量性状基因座。鉴于最近海藻糖磷酸酶基因与作物产量相关的例子，还将注意在海藻糖途径基因中发现SNPs，作为潜在的遗传变异。IWYP中心的成果将用于设计战略性杂交，最大限度地实现源和库的遗传互补性，通过国际小麦改良网络向发达国家和发展中国家的育种人员提供高产。

项目成果

Gene-based mapping of trehalose biosynthetic pathway genes reveals association with source- and sink-related yield traits in a spring wheat panel.

• DOI: 10.1002/fes3.292
• 发表时间: 2021-08
• 期刊: Food and energy security
• 影响因子: 5
• 作者: Lyra DH;Griffiths CA;Watson A;Joynson R;Molero G;Igna AA;Hassani-Pak K;Reynolds MP;Hall A;Paul MJ
• 通讯作者: Paul MJ

Improving rice photosynthesis and yield through trehalose 6-phosphate signaling.

通过海藻糖 6-磷酸信号传导提高水稻光合作用和产量。

• DOI: 10.1016/j.molp.2022.03.004
• 发表时间: 2022
• 期刊: Molecular plant
• 影响因子: 27.5
• 作者: Paul MJ

Sucrose homeostasis: Mechanisms and opportunity in crop yield improvement

• DOI: 10.1016/j.jplph.2024.154188
• 发表时间: 2024-01-31
• 期刊: JOURNAL OF PLANT PHYSIOLOGY
• 影响因子: 4.3
• 作者: Miret，Javier A.;Griffiths，Cara A.;Paul，Matthew J.
• 通讯作者: Paul，Matthew J.

What are the regulatory targets for intervention in assimilate partitioning to improve crop yield and resilience?

• DOI: 10.1016/j.jplph.2021.153537
• 发表时间: 2021-09
• 期刊: Journal of plant physiology
• 影响因子: 4.3
• 作者: M. Paul

Trehalose 6-phosphate signalling and impact on crop yield.

• DOI: 10.1042/bst20200286
• 发表时间: 2020-10-30
• 期刊: Biochemical Society transactions
• 影响因子: 3.9
• 作者: Paul MJ;Watson A;Griffiths CA
• 通讯作者: Griffiths CA