Longitudinal assessment of healthy brain structure and function across the lifespan using 9.4T Magnetic Resonance Imaging

利用磁共振成像技术对人类和动物的大脑进行实时成像，已经提供了关于整个生命周期中大脑结构和功能特性的丰富信息，并确定了与疾病相关的标记。这种专门的成像模式还可以了解不同发展和老龄化时期人群的机制和差异。为了使这项研究处于世界领先地位，需要最高分辨率的扫描仪来提供组织结构和组成的准确细节。我们有一个优秀的，集成的人类和动物脑成像基础设施，但我们的旧的，动物MRI扫描仪需要更换和升级，使我们能够看到大脑结构，功能，组成和连接的较小变化，并确保我们的转化研究仍然是世界一流的。

Live Imaging of the human and animal brain, using Magnetic Resonance Imaging, has provided a wealth of information regarding the structural and functional properties of the brain across the lifespan, and identified markers associated with disease. Such specialised imaging modalities can also inform on the mechanisms and variance within populations across development and ageing. For this research to be world leading, the highest resolution scanners are required to provide accurate details of tissue structure and composition. We have an excellent, integrated infrastructure for human and animal brain imaging, but our old, animal MRI scanner needs to be replaced and upgraded, to allow us to see smaller changes in the brain structure, function, composition and connectivity and ensure our translational research remains world class.