GENETIC STUDIES WITH TETRAHYMENA

四膜虫的遗传学研究

• 批准号: 3267966
• 负责人: DAVID L NANNEY
• 金额: $ 19.48万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 1976
• 资助国家: 美国
• 起止时间: 1976-09-01 至 1987-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3267966
• 关键词: alleles; biochemical evolution; biological polymorphism; cell differentiation; chromatography; cytogenetics; electron microscopy; electrophoresis; evolution; gene expression; genetic mapping; genetic regulation; histogenesis; isozymes; microorganism conjugation; microorganism growth; nucleic acid structure; species difference

This project is directed to the development of utilization of the ciliated protozoa as instruments of scientific analysis. It focuses on the Tetrahymena pyriformis complex that consists of at least 18 genetically isolated gene pools. All the species are used in comparative and evolutionary studies and intensive genetic analysis is applied to two species with apparently very different genetic economies: T. theromphila and T. pigmentosa. Within the Species we are concerned with the regulation of genetic function, and particularly with the changes in genetic function and organization associated with macronuclear development. We are particularly concerned with mating types, antigens, and isozymes.

本项目旨在开发利用纤毛虫 原生动物作为科学分析的工具。 它侧重于 梨形四膜虫复合体，由至少18个基因组成， 孤立的基因库 所有物种都用于比较和 进化研究和密集的遗传分析应用于两个 具有明显不同遗传经济的物种：T.嗜热植物 和T.色素沉着。 在物种内部，我们关注的是 尤其是基因功能的改变 与大核发育相关的组织。 我们 特别是与交配类型、抗原和同工酶有关。