GENETIC STUDIES WITH TETRAHYMENA

四膜虫的遗传学研究

• 批准号: 3267967
• 负责人: DAVID L NANNEY
• 金额: $ 18.13万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 1976
• 资助国家: 美国
• 起止时间: 1976-09-01 至 1987-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3267967
• 关键词: alleles; biochemical evolution; biological polymorphism; cell differentiation; chromatography; cytogenetics; electron microscopy; electrophoresis; evolution; gene expression; genetic mapping; genetic regulation; histogenesis; isozymes; microorganism conjugation; microorganism growth; nucleic acid structure; species difference

This project is directed to the development of utilization of the ciliated protozoa as instruments of scientific analysis. It focuses on the Tetrahymena pyriformis complex that consists of at least 18 genetically isolated gene pools. All the species are used in comparative and evolutionary studies and intensive genetic analysis is applied to two species with apparently very different genetic economies: T. theromphila and T. pigmentosa. Within the Species we are concerned with the regulation of genetic function, and particularly with the changes in genetic function and organization associated with macronuclear development. We are particularly concerned with mating types, antigens, and isozymes.

本项目是针对纤毛虫利用的开发。 原生动物作为科学分析的工具。它的重点是 梨形四膜虫复合体，至少由18个基因组成 孤立的基因库。所有的物种都被用于比较和 进化研究和密集的遗传分析被应用于两个 具有明显不同遗传经济的物种：嗜热圆线虫 和色泽毛霉T.linentosa。在物种内部，我们关心的是规则 遗传功能的变化，特别是遗传功能的变化 以及与大核发育相关的组织。我们是 尤其与交配类型、抗原和同工酶有关。