Understanding how food and beverages deliver improved nutrition across the lifecourse

了解食品和饮料如何在整个生命周期提供改善的营养

• 批准号: BB/X010821/1
• 负责人: Philip Calder
• 金额: $ 45.38万
• 依托单位: University of Southampton
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FX010821%2F1
• 关键词: Understanding; how; food; beverages; deliver

As people age the ability of their body to function can decline. This is most obvious for their muscles and bones and cognition but metabolism and immunity decline as well as do a lot of other body structures and functions. Because this decline in function worsens older people's health and well-being, we call the changes unhealthy ageing. Instead of this, we want to promote healthy ageing, because that means older people stay well. Diet is really important in affecting how fast our body's systems decline as we age. In addition, we now know that things that happen to people when they are young, even before they are born or when they are babies, not only affect their health when they are infants or children, but can carry over into later life. In fact, early life events can influence how fast we show the functional decline of ageing. Again, diet turns out to be really important. The diet of a woman when she is pregnant or breastfeeding and the diet of babies and children not only has immediate effects but has a long-lasting effect. So our early diet sets us up for what happens later on. We need to know more about the influence of a person's diet throughout their whole life on how well they grow, develop and function and then how quickly their function declines as they age. Once we know more about this, we can take steps to make sure that people eat the best foods and meals to ensure heathy ageing. To do this we need to study the effect of meals, individual foods and drinks, and specific nutrients and other components of foods on the body right across the lifecourse. To enable that to happen, scientists who understand how nutrition affects the body have to work more closely with industry who produce the foods that people eat. Ultimately, we need to make these foods more healthy. To do that, we need to carry out research so we know what is healthy at different stages of the lifecourse and also to know whether different people actually respond better (or worse) to different foods and food components. We plan to set up a series of partnerships linking researchers from universities with people from industry to foster better working together so that they can carry out the required research. Our ultimate aim is to create what we call an "Innovation Hub" that enables collaborative research involving academic researchers and industry that will in the end result in industry providing more healthful foods to the consumer, so promoting health across the lifecourse including in older age. To do this each year for five years we will distribute funds for research to researcher-industry partnerships. In some cases, industry will also need to put money into the research. So that the partnerships can be created, we will host workshops where researchers and industry can network and discuss their ideas. Once the funds are awarded for research, we will make sure that the research goes as well as it can. Some of the funds we distribute will be for researchers from universities to spend time in industry or for people from industry to spend time with a researcher at a university. These funds will be very appealing to researchers at an early stage in their career. They will really benefit from exchanging knowledge, getting new skills and having new work-place experiences. These things could be of huge benefit to their career. In this way, we hope to create a better skilled, more knowledgeable and engaged work force to carry out important research that will both give industry the opportunity to have more healthy products and enable the population to be more healthy as they age.

随着人们年龄的增长，他们身体机能的能力会下降。这对他们的肌肉、骨骼和认知能力来说是最明显的，但新陈代谢和免疫力也会下降，许多其他身体结构和功能也会下降。因为这种功能的下降恶化了老年人的健康和福祉，我们称这种变化为不健康老龄化。相反，我们希望促进健康老龄化，因为这意味着老年人保持健康。随着年龄的增长，饮食在影响我们身体系统衰退的速度方面真的很重要。此外，我们现在知道，人们在年轻时，甚至在他们出生前或婴儿时期发生的事情，不仅会影响他们在婴儿或儿童时期的健康，而且会延续到以后的生活中。事实上，早期生活事件会影响我们衰老的功能衰退的速度。再一次，饮食证明是非常重要的。妇女在怀孕或哺乳期间的饮食以及婴儿和儿童的饮食不仅有直接的影响，而且有长期的影响。因此，我们早期的饮食习惯为我们以后的情况做好了准备。我们需要更多地了解一个人一生中饮食对他们生长、发育和功能的影响，以及随着年龄的增长，他们的功能衰退的速度。一旦我们对这一点有了更多的了解，我们就可以采取措施确保人们吃最好的食物和膳食，以确保健康的老龄化。要做到这一点，我们需要研究膳食、个别食物和饮料、特定营养素和食物的其他成分在整个生命过程中对身体的影响。为了实现这一目标，了解营养如何影响人体的科学家必须与生产人们食用食品的企业更密切地合作。最终，我们需要让这些食物更健康。要做到这一点，我们需要进行研究，这样我们就能知道在生命过程的不同阶段什么是健康的，也能知道不同的人对不同的食物和食物成分的反应是否更好（或更差）。我们计划建立一系列伙伴关系，将大学的研究人员与工业界的人员联系起来，以促进更好的合作，使他们能够开展所需的研究。我们的最终目标是创建一个所谓的“创新中心”，使学术研究人员和工业界能够进行合作研究，最终使工业界为消费者提供更健康的食品，从而促进包括老年人在内的整个生命过程中的健康。为了做到这一点，我们将在五年内每年向研究人员与行业合作伙伴分配研究资金。在某些情况下，工业界还需要为研究投入资金。为了建立伙伴关系，我们将举办研讨会，使研究人员和工业界能够建立联系并讨论他们的想法。一旦研究经费被授予，我们将确保研究工作尽可能顺利地进行。我们分配的一些资金将用于大学的研究人员在工业领域进行研究，或者用于工业领域的人员与大学的研究人员进行研究。这些基金将对处于职业生涯早期阶段的研究人员非常有吸引力。他们将真正受益于交流知识，获得新的技能和新的工作经验。这些事情可能对他们的职业生涯有巨大的好处。通过这种方式，我们希望创造一支技能更好、知识更渊博、更敬业的工作队伍，来开展重要的研究，这将使工业界有机会拥有更多健康的产品，并使人们随着年龄的增长更健康。

项目成果

Translational research to identify solutions to the UK's key diet, health and nutrition challenges: The Diet and Health Open Innovation Research Club Innovation Hubs.

旨在确定英国主要饮食、健康和营养挑战解决方案的转化研究：饮食和健康开放创新研究俱乐部创新中心。

• DOI: 10.1111/nbu.12637
• 发表时间: 2023
• 期刊: Nutrition bulletin
• 影响因子: 3.3
• 作者: Stanner S