STAR | Start Healthy - Stay Healthy | Aligning Public and Planetary Health Through Precision Plant-Based Dietary Solutions across the Life-course

明星|

• 批准号: BB/X010872/1
• 负责人: Kourosh Ahmadi
• 金额: $ 46.66万
• 依托单位: University of Surrey
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FX010872%2F1
• 关键词: STAR; Start; Healthy; Stay; Aligning

The global population is living longer but not aging healthier. By 2025, 1.2 billion people globally will be aged over 60 years. Dementia and mental health disorders are two of the greatest causes of disability worldwide. In the UK, 1 in 14 people aged over 65 years and 1 in 6 of those over 80 years have dementia. Mental health disorders are ubiquitous and 1 in 6 adults are likely to experience mental health difficulties. Data from NHS surveying children and adolescents showed that 1 in 6 had a probable mental health problem. Preserving cognitive function, delaying the onset of dementia and preserving mental health are critical public-health (PH) issues to minimise in order to reduce healthcare costs, patient disability, institutionalisation, and mortality. In recognition of the importance of these health issues, the UK government has included dementia and mental health as priority alongside cancer, aging and respiratory diseases (Life Sciences Vision: Build Back Better). Diet is the most modifiable lifestyle factor in reducing the burden of diseases of aging (heart disease, stroke, cancer, dementia) and important for preventing the development of related risk factors (hypertension, poor immune health, mental health, and cognitive decline). Moving our diets towards more plant-based dietary (PBDs) alternatives is also gaining traction as a healthier and more sustainable solution to the strain on global supply chains caused by the increased cost of food coupled with an aging population. To this end, we propose the STAR Hub - Start Healthy-Stay Healthy: Aligning Public and Planetary Health Through Precision Plant-Based Dietary Solutions across the Life-course. Led by the Universities of Surrey, Ulster, Newcastle, and Reading, the Hub brings together at inception national leaders in Nutrition & Health from 12 other UK Universities, 21 Food Industry partners, ranging from UK SMEs to global Large Businesses, end-users and wider stakeholders in the food and drink sector. Together we will tackle this challenge and work towards producing new, sustainable - environmentally friendly -, safe and affordable PBD products that aim to reduce the burden of cognitive decline, dementia and mental health disorders in the population, one of the greatest nutrition and health challenges of our time. Our proposal specifically aligns with Theme 5: Understanding how food and beverages can deliver improved nutrition across the life-course, but links to all the strategic themes of this call. Our overall aim is to provide a better understanding of how food, and the nutrients it contains, can improve metabolic, biological, and physiological processes, and thus generate robust evidence to support novel and innovative dietary solutions that can translate to better mental and cognitive health of individuals throughout life (pregnancy, lactation, childhood, middle and older age). We will broker new partnerships of academia with businesses and co-design new projects to:(1) Provide robust evidence to industry on the role of specific food components in cognitive and mental health across the lifespan; (2) Highlight opportunities for UK-based industry to exploit this evidence through further R&D, ultimately producing new innovative PB dietary products;(3) To target and tailor these products to specific life stages to improve and maintain cognitive/mental health across the life-course. The participants of the Hub have complementary expertise with a track record of successful academic-industry partnerships and the leadership to address one of the important nutrition challenges of our time and generate research outcomes and impacts to inform UK policy and develop future leaders in the food sector. The STAR Hub meets with the scope and vision of the call, to help bridge the gap between bioscience research and translation, and strengthen the diet and health community by building capacity and capability in industry-relevant areas.

全球人口寿命更长，但没有更健康地老龄化。到2025年，全球将有12亿人超过60岁。痴呆症和精神健康障碍是世界范围内残疾的两个最大原因。在英国，每14个65岁以上的人中就有1个，每6个80岁以上的人中就有1个患有痴呆症。心理健康障碍是普遍存在的，六分之一的成年人可能会遇到心理健康问题。NHS调查儿童和青少年的数据显示，六分之一的人可能有心理健康问题。保持认知功能，延迟痴呆症的发作和保持心理健康是关键的公共卫生（PH）问题，以减少医疗保健成本，患者残疾，机构化和死亡率。认识到这些健康问题的重要性，英国政府将痴呆症和精神健康与癌症、衰老和呼吸系统疾病一起列为优先事项（生命科学愿景：重建更好）。饮食是减少老年疾病（心脏病，中风，癌症，痴呆症）负担的最可改变的生活方式因素，对于预防相关风险因素（高血压，免疫健康状况差，心理健康和认知能力下降）的发展非常重要。将我们的饮食转向更多的植物性饮食（PBD）替代品也越来越受到关注，因为这是一种更健康，更可持续的解决方案，可以解决食品成本增加和人口老龄化对全球供应链造成的压力。为此，我们提出了星星枢纽-开始健康，保持健康：通过精确的植物为基础的饮食解决方案，在整个生命过程中，调整公众和地球的健康。由萨里大学，阿尔斯特大学，纽卡斯尔大学和阅读大学领导，该中心汇集了来自其他12所英国大学，21个食品行业合作伙伴的营养与健康国家领导人，从英国中小企业到全球大型企业，最终用户和食品饮料行业的更广泛的利益相关者。我们将共同应对这一挑战，并致力于生产新的，可持续的，环保的，安全的和负担得起的PBD产品，旨在减轻人口中认知能力下降，痴呆症和精神健康障碍的负担，这是我们这个时代最大的营养和健康挑战之一。我们的提案特别符合主题5：了解食品和饮料如何在整个生命过程中提供更好的营养，但与本次呼吁的所有战略主题相关。我们的总体目标是更好地了解食物及其所含的营养素如何改善代谢，生物和生理过程，从而产生强有力的证据来支持新颖和创新的饮食解决方案，这些解决方案可以转化为更好的心理和认知健康的个体在整个生命（怀孕，哺乳，儿童，中年和老年）。我们将促成学术界与企业建立新的合作伙伴关系，并共同设计新项目，以：（1）为工业界提供关于特定食物成分在整个生命周期中对认知和心理健康的作用的有力证据;（2）为英国工业界提供机会，通过进一步的研发利用这一证据，最终生产新的创新PB膳食产品;（3）针对特定的生命阶段，定制这些产品，以改善和维持整个生命过程中的认知/心理健康。该中心的参与者具有互补的专业知识，具有成功的学术-行业合作伙伴关系的良好记录，并具有解决我们这个时代重要营养挑战之一的领导能力，并产生研究成果和影响，为英国政策提供信息，并培养食品行业的未来领导者。该星星枢纽满足了呼吁的范围和愿景，以帮助弥合生物科学研究和翻译之间的差距，并通过在行业相关领域建立能力和能力来加强饮食和健康社区。

项目成果

Translational research to identify solutions to the UK's key diet, health and nutrition challenges: The Diet and Health Open Innovation Research Club Innovation Hubs.

旨在确定英国主要饮食、健康和营养挑战解决方案的转化研究：饮食和健康开放创新研究俱乐部创新中心。

• DOI: 10.1111/nbu.12637
• 发表时间: 2023
• 期刊: Nutrition bulletin
• 影响因子: 3.3
• 作者: Stanner S