STAR | Start Healthy - Stay Healthy | Aligning Public and Planetary Health Through Precision Plant-Based Dietary Solutions across the Life-course

明星|

• 批准号: BB/X010872/1
• 负责人: Kourosh Ahmadi
• 金额: $ 46.66万
• 依托单位: University of Surrey
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FX010872%2F1
• 关键词: STAR; Start; Healthy; Stay; Aligning

The global population is living longer but not aging healthier. By 2025, 1.2 billion people globally will be aged over 60 years. Dementia and mental health disorders are two of the greatest causes of disability worldwide. In the UK, 1 in 14 people aged over 65 years and 1 in 6 of those over 80 years have dementia. Mental health disorders are ubiquitous and 1 in 6 adults are likely to experience mental health difficulties. Data from NHS surveying children and adolescents showed that 1 in 6 had a probable mental health problem. Preserving cognitive function, delaying the onset of dementia and preserving mental health are critical public-health (PH) issues to minimise in order to reduce healthcare costs, patient disability, institutionalisation, and mortality. In recognition of the importance of these health issues, the UK government has included dementia and mental health as priority alongside cancer, aging and respiratory diseases (Life Sciences Vision: Build Back Better). Diet is the most modifiable lifestyle factor in reducing the burden of diseases of aging (heart disease, stroke, cancer, dementia) and important for preventing the development of related risk factors (hypertension, poor immune health, mental health, and cognitive decline). Moving our diets towards more plant-based dietary (PBDs) alternatives is also gaining traction as a healthier and more sustainable solution to the strain on global supply chains caused by the increased cost of food coupled with an aging population. To this end, we propose the STAR Hub - Start Healthy-Stay Healthy: Aligning Public and Planetary Health Through Precision Plant-Based Dietary Solutions across the Life-course. Led by the Universities of Surrey, Ulster, Newcastle, and Reading, the Hub brings together at inception national leaders in Nutrition & Health from 12 other UK Universities, 21 Food Industry partners, ranging from UK SMEs to global Large Businesses, end-users and wider stakeholders in the food and drink sector. Together we will tackle this challenge and work towards producing new, sustainable - environmentally friendly -, safe and affordable PBD products that aim to reduce the burden of cognitive decline, dementia and mental health disorders in the population, one of the greatest nutrition and health challenges of our time. Our proposal specifically aligns with Theme 5: Understanding how food and beverages can deliver improved nutrition across the life-course, but links to all the strategic themes of this call. Our overall aim is to provide a better understanding of how food, and the nutrients it contains, can improve metabolic, biological, and physiological processes, and thus generate robust evidence to support novel and innovative dietary solutions that can translate to better mental and cognitive health of individuals throughout life (pregnancy, lactation, childhood, middle and older age). We will broker new partnerships of academia with businesses and co-design new projects to:(1) Provide robust evidence to industry on the role of specific food components in cognitive and mental health across the lifespan; (2) Highlight opportunities for UK-based industry to exploit this evidence through further R&D, ultimately producing new innovative PB dietary products;(3) To target and tailor these products to specific life stages to improve and maintain cognitive/mental health across the life-course. The participants of the Hub have complementary expertise with a track record of successful academic-industry partnerships and the leadership to address one of the important nutrition challenges of our time and generate research outcomes and impacts to inform UK policy and develop future leaders in the food sector. The STAR Hub meets with the scope and vision of the call, to help bridge the gap between bioscience research and translation, and strengthen the diet and health community by building capacity and capability in industry-relevant areas.

全球人口的寿命越来越长，但老龄化却没有变得更健康。到2025年，全球60岁以上人口将达到12亿。痴呆症和精神健康障碍是全世界致残的两大原因。在英国，65岁以上的人中有1 / 14,80岁以上的人中有1 / 6患有痴呆症。精神健康障碍无处不在，六分之一的成年人可能会遇到精神健康问题。英国国家医疗服务体系调查儿童和青少年的数据显示，六分之一的人可能有精神健康问题。保持认知功能、延缓痴呆症的发病和保持精神健康是关键的公共卫生问题，为了减少医疗保健费用、患者残疾、机构和死亡率，应尽量减少这些问题。认识到这些健康问题的重要性，英国政府将痴呆症和心理健康与癌症、衰老和呼吸系统疾病一起列为优先事项（生命科学愿景：重建得更好）。饮食是减少老年疾病（心脏病、中风、癌症、痴呆）负担的最可改变的生活方式因素，对预防相关风险因素（高血压、免疫健康不良、精神健康和认知能力下降）的发展也很重要。将我们的饮食转向更多的植物性饮食（pbd）替代品，作为一种更健康、更可持续的解决方案，也正受到越来越多的关注，以应对食品成本上升和人口老龄化对全球供应链造成的压力。为此，我们提出了STAR中心-开始健康-保持健康：在整个生命过程中通过精确的植物性饮食解决方案调整公众和地球健康。该中心由萨里大学、阿尔斯特大学、纽卡斯尔大学和雷丁大学领导，从一开始就汇集了来自其他12所英国大学的营养与健康领域的国家领导者，21个食品工业合作伙伴，从英国中小企业到全球大型企业，最终用户以及食品和饮料行业的更广泛利益相关者。我们将共同应对这一挑战，努力生产新的、可持续的、环保的、安全和负担得起的PBD产品，旨在减轻人们认知能力下降、痴呆和精神健康障碍的负担，这是我们这个时代最大的营养和健康挑战之一。我们的提案特别符合主题5：了解食品和饮料如何在整个生命过程中提供更好的营养，但与本次呼吁的所有战略主题都有联系。我们的总体目标是更好地了解食物及其所含营养物质如何改善代谢、生物和生理过程，从而产生强有力的证据来支持新颖和创新的饮食解决方案，这些解决方案可以转化为个体在整个生命周期（怀孕、哺乳、童年、中年和老年）更好的心理和认知健康。我们将促成学术界与企业建立新的伙伴关系，并共同设计新的项目，以便：(1)向工业界提供有关特定食物成分在整个生命周期中对认知和心理健康的作用的有力证据；(2)强调英国产业通过进一步研发利用这一证据的机会，最终生产出新的创新型PB膳食产品；(3)针对特定的生命阶段定制这些产品，以改善和维持整个生命过程中的认知/心理健康。该中心的参与者具有互补的专业知识，具有成功的学术与行业合作伙伴关系的记录，并具有解决我们这个时代重要的营养挑战之一的领导力，并产生研究成果和影响，为英国政策提供信息，并培养未来食品行业的领导者。STAR中心符合这一呼吁的范围和愿景，帮助弥合生物科学研究和转化之间的差距，并通过建设与产业相关领域的能力和能力来加强饮食和健康社区。

项目成果

Translational research to identify solutions to the UK's key diet, health and nutrition challenges: The Diet and Health Open Innovation Research Club Innovation Hubs.

旨在确定英国主要饮食、健康和营养挑战解决方案的转化研究：饮食和健康开放创新研究俱乐部创新中心。

• DOI: 10.1111/nbu.12637
• 发表时间: 2023
• 期刊: Nutrition bulletin
• 影响因子: 3.3
• 作者: Stanner S