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Magnetic Resonance: From the Laboratory to Industrial Practice

磁共振：从实验室到工业实践

基本信息

批准号：
EP/F047991/1
负责人：
Lynn Gladden
金额：
$ 100.54万
依托单位：
University of Cambridge
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2009
资助国家：
英国
起止时间：
2009 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=EP%2FF047991%2F1
关键词：
Magnetic Resonance Laboratory Industrial Practice

项目摘要

Magnetic Resonance Imaging is widely used in hospitals to image blood flow and the internal structure of the human body. Our work focuses on extending these magnetic resonance (MR) techniques to study chemical products and processes. Over the past 5 years we have established an internationally respected skill base in developing MR techniques to study transport in porous materials (e.g. oil flow in rocks), transport and reaction in 3-D systems (e.g. chemical conversion occurring inside catalytic reactors) and processing structure-function relationships (e.g. effect of extrusion processing on the structure and texture of food products). We believe that we now have the research base in place to make a step-change in exploiting MR in industrial practice. To achieve this, we wish to extend our research activities by (i) improving signal-to-noise ratios and speeding up data acquisition times such that we will be able to image hydrodynamics and chemical conversion over much shorter timescales than we can now; our target is to reduce data acquisition times by an order of magnitude; and (ii) developing robust methods for mapping pH, oxygen content, temperature and pressure, and constructing realistic process environments (e.g. elevated pressure and temperature) within the MR magnet. As well as being able to make new measurements under realistic process conditions, these data will also enable us to understand the microscopic physical and chemical processes occurring in these complex systems such that we can work with those developing numerical codes of chemical processes to improve and validate the scientific assumptions and models incorporated in their process design tools. Finally, in collaboration with experts in low-field MR hardware (which is cheap, compact and relatively maintenance free compared with high-field technology) we will bring together our advances in reduced data acquisitions times and signal enhancement with their magnet technology to demonstrate MR measurements in the industrial R&D laboratory and eventually on plant.

磁共振成像广泛应用于医院，以对血流和人体内部结构进行成像。我们的工作重点是将这些磁共振 (MR) 技术扩展到研究化学产品和工艺。在过去的 5 年里，我们在开发 MR 技术方面建立了国际公认的技能基础，以研究多孔材料中的传输（例如岩石中的石油流动）、3D 系统中的传输和反应（例如催化反应器内发生的化学转化）以及加工结构-功能关系（例如挤压加工对食品结构和质地的影响）。我们相信，我们现在已经具备了研究基础，可以在工业实践中利用混合现实做出重大改变。为了实现这一目标，我们希望通过以下方式扩展我们的研究活动：（i）提高信噪比并加快数据采集时间，以便我们能够在比现在短得多的时间尺度内对流体动力学和化学转化进行成像；我们的目标是将数据采集时间减少一个数量级； (ii) 开发强大的方法来绘制 pH、氧含量、温度和压力图，并在 MR 磁体内构建真实的过程环境（例如升高的压力和温度）。除了能够在现实的过程条件下进行新的测量之外，这些数据还将使我们能够了解这些复杂系统中发生的微观物理和化学过程，以便我们可以与开发化学过程数字代码的人员合作，以改进和验证其过程设计工具中纳入的科学假设和模型。最后，与低场 MR 硬件（与高场技术相比便宜、紧凑且相对免维护）专家合作，我们将利用他们的磁铁技术，将我们在缩短数据采集时间和信号增强方面的进步结合起来，在工业研发实验室以及最终在工厂中演示 MR 测量。