权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

VESTIBULAR STIMULATION AND RETARDED INFANT DEVELOPMENT

前庭刺激和婴儿发育迟缓

基本信息

批准号：
3314637
负责人：
William E. MacLean
金额：
$ 9.8万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1984
资助国家：
美国
起止时间：
1984-01-01 至 1987-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3314637
关键词：
Downs syndrome cerebral palsy child mental disorders infant human (0-1 year) mental retardation reflex disorder vestibuloocular reflex

项目摘要

Slowed motor development is a well-known phenomenon among children who suffer varied birth defects and developmental disabilities. Few treatments have been identified that will reliably and significantly enhance the motor and reflex development of disabled babies. However, recent studies indicate that specific rotational vestibular stimulation may produce positive changes in motor and reflex development among delayed infants. Preliminary evidence suggests that some preambulatory children exhibiting Down syndrome, cerebral palsy, and undifferentiated birth defects improve significantly in motor and reflex development following a regimen of semicircular canal stimulation. The purposes of this project are: (a) to study the effects of vestibular stimulation in three groups of babies (normally developing, Down syndrome, and cerebral palsy) with sample sizes sufficient to make inferences about differential responsivity to vestibular stimulation, (b) to study these babies longitudinally in order to separate treatment effects from maturational variables and to determine the long-term effects of the intervention, (c) to measure motor, reflex, physiological and cognitive functions, and (d) to study the relationship between motor development and the stereotyped movements of the babies. 20 Down syndrome, 20 cerebral palsy, and 20 normally developing preambulatory babies between .5 and 2.5 years will serve as subjects in a cross-over longitudinal design that will permit between-groups and within-subjects comparisons. The project will consist of two phases, with half of each subject population in each phase. During the second phase, the subjects will be followed at 3-month intervals to ascertain the long-term effects of the vestibular treatment. Pretest, interim, and posttest measures include motor and reflex scales, an environmental interest inventory, the Bayley Scales, parent questionnaires, and several physiological measures including postrotary nystagmus, heart rate, heart rate variability, respiration, blood pressure, weight and muscle tone. A treatment session of vestibular stimulation consists of rotating the child 10 one-minute periods of rotation in different body positions in a motorized apparatus. Sessions will be conducted 10 times over 2 weeks, on 4 different occasions during the experimental phase.

运动发育缓慢是一个众所周知的现象，患有各种先天缺陷和发育障碍。很少治疗已经确定，将可靠和显着提高电机以及残疾婴儿的反射发育。但最近的研究表明特定旋转前庭刺激可能产生迟发儿运动和反射发育的积极变化。初步证据表明，一些表现出唐氏综合征、脑瘫和未分化出生缺陷改善在运动和反射发育方面，半规管刺激。该项目的目的是：（a）研究前庭刺激对三组婴儿的影响（正常发育，唐氏综合征和脑瘫）与样本量足以对前庭神经刺激的不同反应性做出推断。刺激，（B）纵向研究这些婴儿，以便分离从成熟变量的治疗效果，并确定干预的长期效果，（c）测量运动，反射，生理和认知功能，以及（d）研究运动发展和婴儿的刻板动作之间的联系。 20 唐氏综合征，20例脑瘫，20例正常发育的 0.5到2.5岁的婴儿将作为交叉实验的对象，纵向设计，允许组间和受试者内比较。该项目将包括两个阶段，每个阶段一半每个阶段的受试者人群。在第二阶段，受试者将每隔3个月进行一次随访，以确定前庭治疗测试前、测试中和测试后的测量包括运动和反射量表，环境利益清单，贝利量表、家长问卷和几项生理指标，包括旋转后眼球震颤，心率，心率变异性，呼吸，血压体重和肌肉张力前庭神经痛的治疗刺激包括旋转儿童10个一分钟的周期，在机动设备中的不同身体位置的旋转。届会议将在两周内进行10次，在4个不同的场合，实验阶段。