HEART AND LUNG INTERACTION IN POST-TRAUMA LUNG EDEMA

创伤后肺水肿中心肺的相互作用

• 批准号: 3334595
• 负责人: RICHARD M PETERS
• 金额: $ 11.85万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1975
• 资助国家: 美国
• 起止时间: 1975-09-01 至 1987-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3334595
• 关键词: adult respiratory distress syndrome; artificial respiration; atelectasis; biological fluid transport; bronchoscopy; burns; cardiac output; cardiovascular disorder; chest injury; human subject; mathematical model; oscillography; pneumothorax disorder; postoperative complications; pulmonary circulation; pulmonary edema; radiography; radiotracer; respiratory airway pressure; respiratory airway volume; respiratory disorder; respiratory function; spirometry; thoracic pressure; thoracic surgery; trauma; vascular endothelium permeability; vascular resistance

Using computerized axial tomography scans of full chest and full chest fluoroscopic magnetic tape recordings, we will measure regional changes in lung volume, mass, and weighted mass. These studies are to determine the effects of trauma and operative injury on chest cage and diaphragmatic motion and gravitational force for fluid filtration and lung expansion. These studies are coordinated with clinical studies to determine optimum treatment of acute post-trauma respiratory insufficiency with the goal of developing decision logic to control therapy; in animals, to assess the effects of gravity and hemodilution on the Starling forces.

使用计算机化的轴向断层扫描胸部和全胸部 荧光镜磁带记录，我们将测量肺的区域变化 体积，质量和加权质量。 这些研究是为了确定 胸部笼子和diaphragmatic运动的创伤和手术损伤以及 液体过滤和肺部膨胀的重力。 这些研究与临床研究协调以确定最佳 治疗急性创伤后呼吸不足的目的 发展决策逻辑以控制治疗；在动物中评估影响 在八哥力量上的重力和血液稀释。

项目成果

Serum oncotic pressure and oncotic-hydrostatic pressure differences in critically ill patients.

危重患者的血清胶体渗透压和胶体渗透压差异。

• 发表时间: 1982
• 期刊: Anesthesia and analgesia
• 影响因子: 5.7
• 作者: Sise,MJ;Shackford,SR;Peters,RM;Virgilio,RW
• 通讯作者: Virgilio,RW

Estimation of the volume of lung below the left atrium using computed tomography.

使用计算机断层扫描估计左心房下方的肺体积。

• DOI: 10.1097/00003246-198603000-00002
• 发表时间: 1986
• 期刊: Critical care medicine
• 影响因子: 8.8
• 作者: Friedman,PJ;Peters,RM;Botkin,MC;Brimm,JE;Meltvedt,RC
• 通讯作者: Meltvedt,RC

Evaluation of splenorrhaphy: a grading system for splenic trauma.

脾脏修补术的评估：脾脏创伤的分级系统。

• 发表时间: 1981
• 期刊: The Journal of trauma
• 作者: Shackford,SR;Sise,MJ;Virgilio,RW;Peters,RM
• 通讯作者: Peters,RM

Complications of the flow-directed pulmonary artery catheter: A prospective analysis in 219 patients.

血流导向肺动脉导管的并发症：219 名患者的前瞻性分析。

• DOI: 10.1097/00003246-198104000-00006
• 发表时间: 1981
• 期刊: Critical care medicine
• 影响因子: 8.8
• 作者: Sise,MJ;Hollingsworth,P;Brimm,JE;Peters,RM;Virgilio,RW;Shackford,SR
• 通讯作者: Shackford,SR

Physical therapy. indications for and effects in surgical patients.

物理疗法。

• DOI: 10.1164/arrd.1980.122.5.147
• 发表时间: 1980
• 期刊: The American review of respiratory disease
• 作者: Peters,RM;Turnier,E
• 通讯作者: Turnier,E