Parental imprinting and epigenetic inheritance in honey bees
Parental imprinting and epigenetic inheritance in honey bees
批准号:
DP150100151
负责人:
Prof Benjamin Oldroyd
金额:
$29.23万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-01-31
中文摘要
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英文摘要
This project aims to uncover the mechanisms behind epigenetic inheritance in bees, providing deep insights into their biology, and develop an outstanding new system for studying epigenetics. There are compelling theoretical and empirical reasons to predict epigenetic inheritance in honey bees. Further, reciprocal crosses reveal strong paternal effects suggesting that males modify their sperm to increase the reproductive success of their female offspring. Modification of DNA by methylation and the transfer of small RNA molecules in eggs or semen are two candidate mechanisms by which queens and drones may manipulate gene expression in their offspring.
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海外基金