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Mechanical Imprinting of Epigenetic Memory in Therapeutic Mesenchymal Stromal Cells

Mechanical Imprinting of Epigenetic Memory in Therapeutic Mesenchymal Stromal Cells
治疗性间充质基质细胞表观遗传记忆的机械印记
批准号:
478875
负责人:
Hinz Boris
金额:
$54.06万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01

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After severe skin injury such as burns our body rapidly but poorly repairs the damage, leaving behind stiff scar tissue. Scarring is a clinical burden because skin is losing vital functions. During normal repair, skin fibroblasts are transiently activated
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Mechanical mechanisms of inflammatory cell attraction to myofibroblasts in collagen matrix - implications for lung fibrosis
  • 批准号:
    357572
  • 项目类别:
    Operating Grants
  • 资助金额:
    $52.39万
  • 财政年份:
    2016
  • 负责人:
    Hinz Boris
  • 依托单位:
Innovative biomechanical and molecular strategies to fight fibrosis
  • 批准号:
    355470
  • 项目类别:
    Operating Grants
  • 资助金额:
    $231.48万
  • 财政年份:
    2016
  • 负责人:
    Hinz Boris
  • 依托单位:
Repurposing biomolecules for the treatment of epidermolysis bullosa
  • 批准号:
    311443
  • 项目类别:
    Operating Grants
  • 资助金额:
    $23.38万
  • 财政年份:
    2014
  • 负责人:
    Hinz Boris
  • 依托单位:
Direct interactions between macrophages and myofibroblasts contribute to lung fibrosis
  • 批准号:
    305556
  • 项目类别:
    Operating Grants
  • 资助金额:
    $51.99万
  • 财政年份:
    2014
  • 负责人:
    Hinz Boris
  • 依托单位:
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