HYPERKINETIC BOYS AND THEIR SIBLINGS S YOUNG ADULTS

这是一项多变量青年成人随访研究的最后阶段。 几个患有多动症/注意力缺陷障碍的男孩样本 (HK/ADD)，他们的非高动力全兄弟和非高动力 志愿同学。所有患者最初在6岁至6岁之间接受评估 12人被转诊到爱荷华大学儿童精神病学诊所；所有人都 被儿童精神病学系/住院医生诊断为HK/ADD的所有人都得到了治疗 Etiher药理(主要使用哌醋甲酯)或 心理上(主要是短期父母和/或教师 咨询)；所有这些都由目前的调查员在 青春期(12-18岁)和/或青壮年(21-23岁)。主 样本是：a)早期服药组(香港/ADD男孩被诊断为 1967-1972年，平均使用哌醋甲酯治疗3年)；b)a 过渡期药物治疗组(香港/ADD男童在1972-1975年和 (C)过渡期未用药组)； (香港/ADD男孩也在1972-1975年间确诊，但由于医生 偏爱，未用精神药物治疗)；和d)晚期未用药 组(香港/ADD男童在19788-1975年期间确诊，未接受治疗 精神药物)。 到本授权期结束时，共有421名男童(提早160人 服药患者，40名过渡期患者，22名过渡期患者 未服药患者，37名晚期未服药患者，104名兄弟，58名 同学)将在他们21岁生日后两年内被看到 并进行了一系列多性状、多方法的测试， 问卷调查和访谈。此外，146人连续提交， 被诊断为游戏室的男孩和他们的100名正常对照组将被跟踪调查 年龄在18到20岁之间。本研究的总体目标是 描述香港/ADD儿童的生活历程，并确定 个体预测因素(如攻击性、智商)和环境 生活差异的预测因素(例如，治疗、父母教养方式) 当然了。一系列多变量分析的结果将提供 对药物和药物之间的各种结果的详细描述 未服用药物的香港/青少年男孩/青少年，与同学和 同级控件。计划中的比较将测试对这些项目的影响 多动症本身的结果；兴奋剂治疗的结果；以及 对药物的反应。建立预测和诊断的方法 残留的ADD/成人MBD将是一个特别令人关注的问题。

This is the final phase of a multivariate young adult follow-up study of several samples of boys with Hyperkinetic/Attention Deficit Disorder (HK/ADD), of their nonhyperkinetic full brothers, and of nonhyperkinetic volunteer classmates. All patients were originally evaluated at ages 6 to 12 as referrals to the University of Iowa child psychiatry clinic; all were diagnosed as HK/ADD by child psychiatry faculty/residents' all were treated eitiher pharmacologically (primarily with methylphenidate) or psychologically (primarily with short-term parent and/or teacher counseling); and all are being followed up by the present investigator at adolescence (ages 12-18) and/or young adulthood (ages 21-23). The main samples are: a) an Early Medicated group (HK/ADD boys diagnosed between 1967-1972 and treated with methylphenidate for an average of 3 years); b) a Transitional Medicated group (HK/ADD boys diagnosed between 1972-1975 and also treated with methylphenidate); c) a Transitional Unmedicated) group (HK/ADD boys also diagnosed between 1972-1975 but, because of physician preference, not treated with psychotropic drugs); and d) a Late Unmedicated group (HK/ADD boys diagnosed between 1975-19788 and not treated with psychotropic drugs). By the end of the present grant period, a total of 421 boys (160 Early Medicated patients, 40 Transitional Medicated patients, 22 Transitional Unmedicated patients, 37 Late Unmedicated patients, 104 brothers, and 58 classmates) will have been seen within two years after their 21st birthday and administered a multitrait and multimethod battery of tests, questionnaires, and interviews. In addition, 146 consecutively-referred, playroom-diagnosed boys and their 100 normal controls will be followed up at between 18 to 20 years of age. The general aim of the present study is to describe the life course of the HK/ADD child and to identify the individual predictors (e.g., aggression, IQ) and the environmental predictors (e.g., treatment, parenting styles) of differences in life course. Results of a series of multivariate analyses will provide a detailed description of a variety of outcomes among both medicated and unmedicated HK/ADD boys as adolescents and young adults, with classmate and sibling controls. Planned comparisons will test the effects on these outcomes of hyperkinesis per se; of stimulant drug treatment; and of response to medication. Establishing means for predicting and diagnosing residual ADD/adult MBD will be a special concern.